Goat anti-Human Protein Phosphatase 4, Regulatory Subunit 3, alpha Polyclonal Antibody | anti-PPP1R7 antibody
Protein Phosphatase 4, Regulatory Subunit 3, alpha (PP4R3 alpha, PP4R3A, PPP4R3A, KIAA2010, FLFL1, MEK1 Suppressor 1, MSTP033, SMEK Homolog 1 Suppressor of Mek1 (Dictyostelium), Smek1, smk1, smk-1)
Gene Names
PPP1R7; SDS22
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity PurifiedPurified by affinity chromatography.
Synonyms
Protein Phosphatase 4; Regulatory Subunit 3; alpha; Polyclonal Antibody; alpha (PP4R3 alpha; PP4R3A; PPP4R3A; KIAA2010; FLFL1; MEK1 Suppressor 1; MSTP033; SMEK Homolog 1 Suppressor of Mek1 (Dictyostelium); Smek1; smk1; smk-1); Anti -Protein Phosphatase 4; anti-PPP1R7 antibody
Host
Goat
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human SMEK1 at ~110kD. Species sequence homology: mouse, rat, canine.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Purified by affinity chromatography.
Form/Format
Supplied as a liquid in Tris, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Applicable Applications for anti-PPP1R7 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:16,000
Western Blot: 0.3-1ug/ml
Dilution: ELISA: 1:16,000
Western Blot: 0.3-1ug/ml
Immunogen
Synthetic peptide, C-EQQRERQDNPKLD, from the internal region of human SMEK1.
Positive Control
Human Pancreas lysates
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 monthsat -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-PPP1R7 antibody
Regulatory subunit of serine/threonine-protein phosphatase 4. May regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Product Categories/Family for anti-PPP1R7 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41,564 Da
NCBI Official Full Name
protein phosphatase 1 regulatory subunit 7 isoform 3
NCBI Official Synonym Full Names
protein phosphatase 1, regulatory subunit 7
NCBI Official Symbol
PPP1R7
NCBI Official Synonym Symbols
SDS22
NCBI Protein Information
protein phosphatase 1 regulatory subunit 7; protein phosphatase 1 regulatory subunit 22; protein phosphatase 1, regulatory (inhibitor) subunit 7
UniProt Protein Name
Protein phosphatase 1 regulatory subunit 7
Protein Family
UniProt Gene Name
PPP1R7
UniProt Synonym Gene Names
SDS22
UniProt Entry Name
PP1R7_HUMAN
NCBI Description
This gene encodes a protein subunit that regulates the activity of the serine/threonine phosphatase, protein phosphatase-1. The encoded protein is required for completion of the mitotic cycle and for targeting protein phosphatase-1 to mitotic kinetochores. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Uniprot Description
PPP1R7: Regulatory subunit of protein phosphatase 1. Belongs to the SDS22 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit
Chromosomal Location of Human Ortholog: 2q37.3
Cellular Component: cytoplasm; chromosome; nucleus
Molecular Function: protein phosphatase type 1 regulator activity; enzyme regulator activity
Biological Process: regulation of catalytic activity; positive regulation of protein amino acid dephosphorylation; chromosome segregation
Research Articles on PPP1R7
Similar Products
Product Notes
The PPP1R7 ppp1r7 (Catalog #AAA628270) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Protein Phosphatase 4, Regulatory Subunit 3, alpha (PP4R3 alpha, PP4R3A, PPP4R3A, KIAA2010, FLFL1, MEK1 Suppressor 1, MSTP033, SMEK Homolog 1 Suppressor of Mek1 (Dictyostelium), Smek1, smk1, smk-1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Protein Phosphatase 4, Regulatory Subunit 3, alpha can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: ELISA: 1:16,000 Western Blot: 0.3-1ug/ml. Researchers should empirically determine the suitability of the PPP1R7 ppp1r7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Protein Phosphatase 4, Regulatory Subunit 3, alpha, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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