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Rabbit Protein Phosphatase 2A, Serine, Threonine Polyclonal Antibody | anti-mts antibody

Protein Phosphatase 2A, Serine, Threonine (PP2A Ser/Thr)

Gene Names
mts; 5559; CG7109; DmelCG7109; DmPp2A-28D; dPP2A; dPP2A-C; ER2-6; l(2)02496; l(2)s5286; Mts; MTS/PP2A; PP2; Pp2A; PP2a; PP2A; PP2a 28D; PP2A 28D; PP2A C; Pp2A-28D; PP2A-C; PP2Ac; PP2A[C]; PP2A[[C]]
Reactivity
Human, Mouse, Rabbit, Rat
Applications
Western Blot, Immunoprecipitation
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
Protein Phosphatase 2A; Serine; Threonine; Polyclonal Antibody; Threonine (PP2A Ser/Thr); Anti -Protein Phosphatase 2A; anti-mts antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rabbit, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human PP-2. Does not crossreact with PP-1 or other protein phosphatases. Species Crossreactivity: mouse, rat and rabbit
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.05% sodium azide.
Applicable Applications for anti-mts antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes
Suitable for use in Western Blot, Immunoprecipitation and Phosphatase assays.
Dilution: Western Blot: 0.5-2ug/ml. Detects PP2A catalytic subunit (~34kD) in rabbit brain membrane cytosol and in human A431 RIPA cell lysate.
Immunoprecipitation: 4ug immunoprecipitates PP2A catalytic subunit from 500ug rabbit brain extract and 1mg human A431 RIPA cell lysate.
Immunoprecipitation/Phosphatase Assay: 5ug immunoprecipitates PP2A from 1U of purified Protein Phosphatase 2A, Serine, Threonine (PP2A Ser/Thr) (Catalog No: P9107-33D). Phospatase activity was demonstrated using Phosphatase Assay Kit Ser/Thr, KR-pT-IRR, BioAssay (Catalog No: P4071-70).
Optimal dilutions to be detemined by the researcher.
Immunogen
Synthetic peptide corresponding to aa296-309 within the C-terminus of human protein phosphatase 2A, conjugated to KLH.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-mts antibody
Type 2 protein phosphatases are serine/threonine phosphatases which can preferentially dephosphorylate the alpha subunit of phosphorylase kinase and are insensitive to inhibitor 2 treatment. Protein phosphatase 2A (PP2A) can be distinguished from PP2B and PP2C which require Ca2+ and Mg2+, respectively, by its partial activity in the absence of divalent cations. PP2A activity is potently inhibited by treatment with okadaic acid and shows much stronger activity toward histone phosphorylated by Protein Kinase C and casein phosphorylated by Protein Kinase A than other protein phosphatases.
Product Categories/Family for anti-mts antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
35,469 Da
NCBI Official Full Name
protein phosphatase 2A
NCBI Official Synonym Full Names
microtubule star
NCBI Official Symbol
mts
NCBI Official Synonym Symbols
5559; CG7109; DmelCG7109; DmPp2A-28D; dPP2A; dPP2A-C; ER2-6; l(2)02496; l(2)s5286; Mts; MTS/PP2A; PP2; Pp2A; PP2a; PP2A; PP2a 28D; PP2A 28D; PP2A C; Pp2A-28D; PP2A-C; PP2Ac; PP2A[C]; PP2A[[C]]
NCBI Protein Information
CG7109 gene product from transcript CG7109-RA; CG7109-PA; PP2A catalytic subunit; catalytic subunit C of type 2A protein phosphatase; microtubule star; mts-PA; phosphatase 2A catalytic subunit; protein phosphatase 2A; protein phosphatase 2A at 28D
UniProt Protein Name
Serine/threonine-protein phosphatase PP2A
UniProt Gene Name
mts
UniProt Synonym Gene Names
PP2A; Pp2A-28D
UniProt Entry Name
PP2A_DROME

Uniprot Description

Catalytic activity: A phosphoprotein + H2O = a protein + phosphate.

Cofactor: Binds 1 iron ion per subunit

By similarity.Binds 1 manganese ion per subunit

By similarity.

Sequence similarities: Belongs to the PPP phosphatase family. PP-2A subfamily.

Research Articles on mts

Similar Products

Product Notes

The mts mts (Catalog #AAA631397) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Protein Phosphatase 2A, Serine, Threonine (PP2A Ser/Thr) reacts with Human, Mouse, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Protein Phosphatase 2A, Serine, Threonine can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP). Suitable for use in Western Blot, Immunoprecipitation and Phosphatase assays. Dilution: Western Blot: 0.5-2ug/ml. Detects PP2A catalytic subunit (~34kD) in rabbit brain membrane cytosol and in human A431 RIPA cell lysate. Immunoprecipitation: 4ug immunoprecipitates PP2A catalytic subunit from 500ug rabbit brain extract and 1mg human A431 RIPA cell lysate. Immunoprecipitation/Phosphatase Assay: 5ug immunoprecipitates PP2A from 1U of purified Protein Phosphatase 2A, Serine, Threonine (PP2A Ser/Thr) (Catalog No: P9107-33D). Phospatase activity was demonstrated using Phosphatase Assay Kit Ser/Thr, KR-pT-IRR, BioAssay (Catalog No: P4071-70). Optimal dilutions to be detemined by the researcher. Researchers should empirically determine the suitability of the mts mts for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Protein Phosphatase 2A, Serine, Threonine, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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