Rabbit anti-Human, Mouse PROS1 Polyclonal Antibody | anti-PROS1 antibody

PROS1 (Vitamin K-dependent Protein S, PROS) APC

Cat. Num. AAA6390924

• Gene Names: PROS1; PSA; PROS; PS21; PS22; PS23; PS24; PS25; THPH5; THPH6
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: PROS1; Polyclonal Antibody; PROS1 (Vitamin K-dependent Protein S; PROS) APC; anti-PROS1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human PROS1. Species Crossreactivity: mouse.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
• Sequence Length: 2432

• Applicable Applications for anti-PROS1 antibody: Western Blot (WB)
• Application Notes: Applications are based on unconjugated antibody.
• Immunogen: Full length human PROS1, aa1-676 (AAH15801.1).
• Immunogen Sequence: MRVLGGRCGALLACLLLVLPVSEANFLSKQQASQVLVRKRRANSLLEETKQGNLERECIEELCNKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYELLYLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIEVQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGLLETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDYNNVSSAEGWHVNVTLNIRPSTGTGVMLALVSGNNTVPFAVSLVDSTSEKSQDILLSVENTVIYRIQALSLCSDQQSHLEFRVNRNNLELSTPLKIETISHEDLQRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVWKKTKNS
• Conjugate: APC
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(PROS1 rabbit polyclonal antibody. Western Blot analysis of PROS1 expression in mouse kidney.)

Western Blot (WB)

(Western Blot analysis of PROS1 expression in transfected 293T cell line by PROS1 polyclonal antibody. Lane 1: PROS1 transfected lysate (75.1kD). Lane 2: Non-transfected lysate.)

Related Product Information for anti-PROS1 antibody

Protein S is a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in Protein S result in autosomal dominant hereditary thrombophilia.

Product Categories/Family for anti-PROS1 antibody

Antibodies; Protein S

NCBI and Uniprot Product Information

• NCBI GI #: 16041821
• NCBI GeneID: 5627
• NCBI Official Full Name: Homo sapiens protein S (alpha), mRNA
• NCBI Official Synonym Full Names: protein S
• NCBI Official Symbol: PROS1
• NCBI Official Synonym Symbols: PSA; PROS; PS21; PS22; PS23; PS24; PS25; THPH5; THPH6
• NCBI Protein Information: vitamin K-dependent protein S
• Protein Family: Proline--tRNA ligase

NCBI Description

This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Oct 2015]