ELISA (EIA)
(Figure 1 ELISA ValidationCoating Antigen: immunogen peptide, 10 μg/mL, incubate at 4 ˚C overnight. Detection Antibodies: SARS-CoV-2 Spike antibody, dilution: 0.5-1000 ng/mL, incubate at RT for 1 hr. was detected by HRP-conjugated streptavidin at 1:5,000 and was detected by anti-rabbit HRP conjugated secondary antibodies at 1:10,000 , incubate at RT for 1 hr.)
Rabbit ACE2 Polyclonal Antibody | anti-ACE2 antibody
ACE2 Antibody (biotin)
The immunogen is located within the last 50 amino acids of ACE2.
ELISA (EIA)
(Figure 1 ELISA ValidationCoating Antigen: immunogen peptide, 10 μg/mL, incubate at 4 ˚C overnight. Detection Antibodies: SARS-CoV-2 Spike antibody, dilution: 0.5-1000 ng/mL, incubate at RT for 1 hr. was detected by HRP-conjugated streptavidin at 1:5,000 and was detected by anti-rabbit HRP conjugated secondary antibodies at 1:10,000 , incubate at RT for 1 hr.)
ELISA (EIA)
(Figure 1 ELISA ValidationCoating Antigen: immunogen peptide, 10 μg/mL, incubate at 4 ˚C overnight. Detection Antibodies: SARS-CoV-2 Spike antibody, dilution: 0.5-1000 ng/mL, incubate at RT for 1 hr. was detected by HRP-conjugated streptavidin at 1:5,000 and was detected by anti-rabbit HRP conjugated secondary antibodies at 1:10,000 , incubate at RT for 1 hr.)
ACE2 Antibody: Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. Homology modeling shows 2019-nCoV has a similar receptor-binding domain structure as SARS-CoV, which suggests COVID-19 (2019-nCoV) may use ACE2 as a receptor in humans for infection. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.
NCBI and Uniprot Product Information
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Product Notes
The ACE2 (Catalog #AAA154836) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's ACE2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the ACE2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ACE2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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