Sheep anti-Human Procalcitonin Polyclonal Antibody | anti-S100a9 antibody

Procalcitonin (PCT)

Cat. Num. AAA623342

• Gene Names: S100a9; Mrp14
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry, Gel Super Shift Assay
• Purity: Purified; Purified
• Synonyms: Procalcitonin; Polyclonal Antibody; Procalcitonin (PCT); Anti -Procalcitonin (PCT); anti-S100a9 antibody

• Host: Sheep
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human Procalctonin.
• Purity/Purification: Purified; Purified
• Form/Format: Supplied as a liquid in 20mM phosphate, 150mM sodium chloride, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-S100a9 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Gel Shift Assay (GS/EMSA)
• Application Notes: Suitable for use in ELISA, Western Blot, Dot Blot, Immunohistochemistry, Immunoassays, development of rapid tests and other antibody recognition assays.
• Immunogen: Recombinant corresponding to aa3-116 from human procalcitonin, fused to 6x His-tag at N-terminal, expressed in E. coli.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Related Product Information for anti-S100a9 antibody

Procalcitonin is a peptide hormone mainly produced by the C cells of the thyroid and certain endocrine cells of the lung. Under normal expression conditions, procalcitonin is immediately cleaved into three specific fragments, an N terminal residue, calcitonin and katacalcin. Levels of unprocessed procalcitonin rise significantly after bacterial infection, trauma or shock.

Product Categories/Family for anti-S100a9 antibody

Antibodies; Abs to Calcitonin

NCBI and Uniprot Product Information

• NCBI GI #: 16758364
• NCBI GeneID: 94195
• NCBI Accession #: NP_446039.1
• NCBI GenBank Nucleotide #: NM_053587.1
• UniProt Accession #: P50116; Q761U7
• Molecular Weight: 13,145 Da
• NCBI Official Full Name: protein S100-A9
• NCBI Official Synonym Full Names: S100 calcium binding protein A9
• NCBI Official Symbol: S100a9
• NCBI Official Synonym Symbols: Mrp14
• NCBI Protein Information: protein S100-A9; p14; MRP-14; calgranulin-B; myeloid-related protein 14; intracellular calcium-binding protein (MRP14); migration inhibitory factor-related protein 14; S100 calcium binding protein A9 (calgranulin B); S100 calcium-binding protein A9 (calgranulin B)
• UniProt Protein Name: Protein S100-A9
• Protein Family: Protein
• UniProt Gene Name: S100a9
• UniProt Synonym Gene Names: Mrp14; MRP-14; p14
• UniProt Entry Name: S10A9_RAT

NCBI Description

calcium binding protein that may be associated with acute inflammatory processes [RGD, Feb 2006]

Uniprot Description

S100A9: a calcium-binding regulatory protein of the S-100 family expressed by macrophages in acutely inflammated tissues and in chronic inflammations. May be an inhibitor of protein kinases. Also expressed in epithelial cells constitutively or induced during dermatoses. May interact with components of the intermediate filaments in monocytes and epithelial cells. Interacts with CEACAM3 in a calcium-dependent manner.

Protein type: Calcium-binding; Motility/polarity/chemotaxis; Cytoskeletal

Cellular Component: extracellular space; cytoskeleton; cytoplasm; plasma membrane; nucleus

Molecular Function: arachidonic acid binding; antioxidant activity; RAGE receptor binding; zinc ion binding; microtubule binding; calcium ion binding

Biological Process: caspase activation; neutrophil chemotaxis; chronic inflammatory response; leukocyte chemotaxis; response to lipopolysaccharide; positive regulation of peptide secretion; leukocyte migration during inflammatory response; response to ethanol; response to zinc ion; actin cytoskeleton reorganization; autophagy; innate immune response; regulation of integrin biosynthetic process; positive regulation of inflammatory response