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Immunohistochemistry (IHC) (Anti-PRLHR / GPR10 antibody IHC of human anterior pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit PRLHR / GPR10 Polyclonal Antibody | anti-PRLHR antibody

Rabbit Polyclonal to Human PRLHR / GPR10

Gene Names
PRLHR; GR3; GPR10; PrRPR
Reactivity
Gorilla, Human, Rat
Predicted Reactivity: Monkey, Mouse, Dog (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry, ELISA
Purity
Immunoaffinity Purified
Synonyms
PRLHR / GPR10; Polyclonal Antibody; Rabbit Polyclonal to Human PRLHR / GPR10; Anti-PRLHR / GPR10 Antibody (Extracellular Domain) IHC-plus; PRLHR; G protein-coupled receptor 10; G-protein coupled receptor 10; GPR10; GR3; HGR3; PrRP receptor; PrRPR; Uhr-1; Human PRLHR; anti-PRLHR antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Gorilla, Human, Rat
Predicted Reactivity: Monkey, Mouse, Dog (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human PRLHR / GPR10. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
370
Applicable Applications for anti-PRLHR antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes
ELISA, IHC-P (20 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
Target Species
Human
Immunogen Description
Synthetic 19 amino acid peptide from 2nd extracellular domain of human PRLHR / GPR10. Percent identity with other species by BLAST analysis: Human, Gorilla, Rat (100%); Monkey, Marmoset, Mouse, Dog, Panda (95%); Bovine, Pig (89%); Horse (84%).
Immunogen Type
Synthetic peptide
Immunogen
PRLHR / GPR10 antibody was raised against synthetic 19 amino acid peptide from 2nd extracellular domain of human PRLHR / GPR10. Percent identity with other species by BLAST analysis: Human, Gorilla, Rat (100%); Monkey, Marmoset, Mouse, Dog, Panda (95%); Bovine, Pig (89%); Horse (84%).
Antigen Modification
Extracellular Domain
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-PRLHR / GPR10 antibody IHC of human anterior pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-PRLHR / GPR10 antibody IHC of human anterior pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-PRLHR antibody
Prolactin releasing hormone receptor (hGR3/GPR10) is a Releasing Hormone Receptor that controls the secretion of prolactin from the anterior pituitary.
Product Categories/Family for anti-PRLHR antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
41,121 Da
NCBI Official Full Name
prolactin-releasing peptide receptor
NCBI Official Synonym Full Names
prolactin releasing hormone receptor
NCBI Official Symbol
PRLHR
NCBI Official Synonym Symbols
GR3; GPR10; PrRPR
NCBI Protein Information
prolactin-releasing peptide receptor; hGR3; prRP receptor; G protein-coupled receptor 10; G-protein coupled receptor 10; prolactin releasing peptide receptor; prolactin-releasing hormone receptor
UniProt Protein Name
Prolactin-releasing peptide receptor
UniProt Gene Name
PRLHR
UniProt Synonym Gene Names
GPR10; GR3; PrRP receptor; PrRPR
UniProt Entry Name
PRLHR_HUMAN

NCBI Description

PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH; MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al., 2002 [PubMed 11923475]).[supplied by OMIM, Mar 2008]

Uniprot Description

GPR10: Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 10q26.13

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; protein binding; neuropeptide receptor activity; neuropeptide Y receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway; hormone metabolic process; feeding behavior; female pregnancy

Research Articles on PRLHR

Similar Products

Product Notes

The PRLHR prlhr (Catalog #AAA240889) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human PRLHR / GPR10 reacts with Gorilla, Human, Rat Predicted Reactivity: Monkey, Mouse, Dog (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's PRLHR / GPR10 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), ELISA (EIA). ELISA, IHC-P (20 ug/ml) Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the PRLHR prlhr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRLHR / GPR10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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