Western Blot (WB)
(Mouse Prkce Antibody (N-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Prkce antibody detected the Prkce protein (arrow).)
Rabbit Prkce Polyclonal Antibody | anti-Prkce antibody
Mouse Prkce Antibody (N-term)
Western Blot (WB)
(Mouse Prkce Antibody (N-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Prkce antibody detected the Prkce protein (arrow).)
Western Blot (WB)
(Mouse Prkce Antibody (N-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Prkce antibody detected the Prkce protein (arrow).)
PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
Roh, D.H., et al. Neurosci. Lett. 477(2):95-99(2010)
Batarseh, A., et al. Biochemistry 49(23):4766-4778(2010)
Fenton, R.A., et al. Am. J. Physiol. Heart Circ. Physiol. 298 (6), H1671-H1678 (2010) :
Gan, L., et al. Mol. Immunol. 47(6):1278-1282(2010)
NCBI and Uniprot Product Information
Uniprot Description
PKCE: an AGC kinase of the PKC family. Calcium-independent, phospholipid-dependent. Activated by inflammatory mediators and involved in nociceptive functions. PKC-epsilon null mice display decreased hypoxic pulmonary vasoconstriction.
Protein type: Protein kinase, AGC; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.13; AGC group; PKC family; Eta subfamily
Cellular Component: Golgi apparatus; mitochondrion; cell; endoplasmic reticulum; cytosol; Golgi membrane; cytoskeleton; membrane; perinuclear region of cytoplasm; cytoplasm; plasma membrane; intracellular; nucleus
Molecular Function: actin monomer binding; protein kinase C activity; metal ion binding; enzyme activator activity; nucleotide binding; ethanol binding; protein kinase binding; receptor activator activity; protein kinase activity; transferase activity; calcium-independent protein kinase C activity; protein serine/threonine kinase activity; protein binding; enzyme binding; transferase activity, transferring phosphorus-containing groups; kinase activity; SH3 domain binding; ATP binding; receptor binding
Biological Process: positive regulation of cytokinesis; positive regulation of catalytic activity; regulation of lipid metabolic process; positive regulation of I-kappaB kinase/NF-kappaB cascade; immune system process; positive regulation of synaptic transmission, GABAergic; positive regulation of insulin secretion; response to morphine; positive regulation of lipid catabolic process; cell cycle; protein amino acid phosphorylation; regulation of release of sequestered calcium ion into cytosol; peptidyl-serine phosphorylation; positive regulation of MAPKKK cascade; positive regulation of actin filament polymerization; cell division; release of sequestered calcium ion into cytosol; negative regulation of release of sequestered calcium ion into cytosol; macrophage activation during immune response; lipopolysaccharide-mediated signaling pathway; chemosensory behavior; reduction of mitochondrial calcium ion concentration; cell adhesion; phosphorylation; regulation of peptidyl-tyrosine phosphorylation; negative regulation of apoptosis
Research Articles on Prkce
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Product Notes
The Prkce prkce (Catalog #AAA9200713) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 123-150. The Mouse Prkce Antibody (N-term) reacts with Mouse (Predicted Reactivity: Human, Rabbit, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's Prkce can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Prkce prkce for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Prkce, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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