Western Blot (WB)
(Western blot analysis of PRKCDBP in A20 cell lysate with PRKCDBP antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Rabbit anti-Human, Mouse PRKCDBP Polyclonal Antibody | anti-PRKCDBP antibody
PRKCDBP Antibody
Gene Names
PRKCDBP; SRBC; HSRBC; CAVIN3; cavin-3
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
PRKCDBP Antibody is affinity chromatography purified via peptide column.
Synonyms
PRKCDBP; Polyclonal Antibody; PRKCDBP Antibody; SRBC; HSRBC; CAVIN3; cavin-3; Protein kinase C delta-binding protein; Cavin-3; hSRBC; protein kinase C; delta binding protei; anti-PRKCDBP antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
It is predicted to not cross-react with other members of the cavin family.
Purity/Purification
PRKCDBP Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
261
Applicable Applications for anti-PRKCDBP antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
PRKCDBP antibody can be used for detection of PRKCDBP by Western blot at 1 - 2 mug/mL.
Conjugate
Unconjugated
Immunogen
Rabbit polyclonal PRKCDBP antibody was raised against an 17 amino acid peptide near the center of human PRKCDBP.
Buffer
PRKCDBP Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
PRKCDBP antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
Western Blot (WB)
(Western blot analysis of PRKCDBP in A20 cell lysate with PRKCDBP antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Western Blot (WB)
(Western blot analysis of PRKCDBP in A20 cell lysate with PRKCDBP antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Immunohistochemistry (IHC)
(Immunohistochemistry of PRKCDBP in human spleen tissue with PRKCDBP antibody at 2.5 μg/ml.)
Immunohistochemistry (IHC)
(Immunohistochemistry of PRKCDBP in human spleen tissue with PRKCDBP antibody at 2.5 μg/ml.)
Immunofluorescence (IF)
(Immunofluorescence of PRKCDBP in human spleen tissue with PRKCDBP antibody at 20 μg/ml.)
Immunofluorescence (IF)
(Immunofluorescence of PRKCDBP in human spleen tissue with PRKCDBP antibody at 20 μg/ml.)
Related Product Information for anti-PRKCDBP antibody
PRKCDBP Antibody: The protein kinase C delta (PKC-δ) binding protein (PRKCDBP), also known as cavin-3, is a member of the cavin family of proteins that are involved in caveolin formation and regulation. PRKCDBP was initially identified in a screen of cultured cell lines for proteins that were strongly induced by serum starvation. Studies indicate that PRKCDBP binds not only to PKC-δ but also to caveolin-1 and helps regulate caveolin traffic and function. Similar to other members of the cavin family, the expression of PRKCDBP was found to be down-regulated in various cancer cell lines, suggesting a possible tumor suppressor function of PRKCDBP.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
29 kDa
NCBI Official Full Name
protein kinase C delta-binding protein
NCBI Official Synonym Full Names
protein kinase C, delta binding protein
NCBI Official Symbol
PRKCDBP
NCBI Official Synonym Symbols
SRBC; HSRBC; CAVIN3; cavin-3
NCBI Protein Information
protein kinase C delta-binding protein; sdr-related gene product that binds to c-kinase; serum deprivation response factor-related gene product that binds to C-kinase
UniProt Protein Name
Protein kinase C delta-binding protein
Protein Family
UniProt Gene Name
PRKCDBP
UniProt Synonym Gene Names
SRBC; hSRBC
UniProt Entry Name
PRDBP_HUMAN
NCBI Description
The protein encoded by this gene was identified as a binding protein of the protein kinase C, delta (PRKCD). The expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor function of this protein. [provided by RefSeq, Jul 2008]
Uniprot Description
PRKCDBP: Seems to have an immune potentiation function. Belongs to the PTRF/SDPR family.
Protein type: Tumor suppressor
Chromosomal Location of Human Ortholog: 11p15.4
Cellular Component: protein complex; cytoplasm; caveola
Molecular Function: protein binding; protein kinase C binding
Biological Process: negative regulation of protein kinase B signaling cascade; cortical actin cytoskeleton organization and biogenesis; circadian regulation of gene expression
Research Articles on PRKCDBP
Similar Products
Product Notes
The PRKCDBP prkcdbp (Catalog #AAA153469) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PRKCDBP Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PRKCDBP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). PRKCDBP antibody can be used for detection of PRKCDBP by Western blot at 1 - 2 mug/mL. Researchers should empirically determine the suitability of the PRKCDBP prkcdbp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRKCDBP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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