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Western Blot (WB) (Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Western Blot Image: Western blot analysis of extracts from K562/HepG2 cells, using PKAR2 beta Antibody. The lane on the right is treated with the synthesized peptide. Requested From: United States Laboratory Reagent)

Rabbit PRKAR2B Polyclonal Antibody | anti-Prkar2b antibody

PRKAR2B, ID (PRKAR2B, cAMP-dependent protein kinase type II-beta regulatory subunit)

Gene Names
Prkar2b; Pkarb2; AI451071; AW061005; RII(beta); PKARIIbeta
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity Purified
Purified by immunoaffinity chromatography
Synonyms
PRKAR2B; Polyclonal Antibody; ID (PRKAR2B; cAMP-dependent protein kinase type II-beta regulatory subunit); Anti -PRKAR2B; anti-Prkar2b antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human PRKAR2B. Species Crossreactivity: Mouse, rat.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography
Form/Format
Supplied as a liquid in PBS, (without Mg2+, Ca2+), pH 7.4, 150mM sodium chloride, 0.02% sodium azide, 50% glycerol.
Applicable Applications for anti-Prkar2b antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Suitable for use in ELISA, Western Blot, Immunohistochemistry.
Dilution: ELISA: 1:1000
Western Blot: 1:500-1:1000
Immunohistochemistry (Paraffin): 10ug/ml
Immunogen
Synthetic peptide corresponding to human PRKAR2B.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Western Blot Image: Western blot analysis of extracts from K562/HepG2 cells, using PKAR2 beta Antibody. The lane on the right is treated with the synthesized peptide. Requested From: United States Laboratory Reagent)

Western Blot (WB) (Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Western Blot Image: Western blot analysis of extracts from K562/HepG2 cells, using PKAR2 beta Antibody. The lane on the right is treated with the synthesized peptide. Requested From: United States Laboratory Reagent)

Western Blot (WB)

(Western blot analysis of extracts from K562/HepG2 cells, using PKAR2 beta. The lane on the right is treated with the synthesized peptide.)

Western Blot (WB) (Western blot analysis of extracts from K562/HepG2 cells, using PKAR2 beta. The lane on the right is treated with the synthesized peptide.)
Related Product Information for anti-Prkar2b antibody
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
Product Categories/Family for anti-Prkar2b antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
46,167 Da
NCBI Official Full Name
Prkar2b protein
NCBI Official Synonym Full Names
protein kinase, cAMP dependent regulatory, type II beta
NCBI Official Symbol
Prkar2b
NCBI Official Synonym Symbols
Pkarb2; AI451071; AW061005; RII(beta); PKARIIbeta
NCBI Protein Information
cAMP-dependent protein kinase type II-beta regulatory subunit
UniProt Protein Name
cAMP-dependent protein kinase type II-beta regulatory subunit
UniProt Gene Name
Prkar2b
UniProt Entry Name
KAP3_MOUSE

Uniprot Description

PKAR2B: a regulatory subunit of cAMP-regulated protein kinase. The inactive form of the enzyme is composed of two regulatory chains and two catalytic chains. Activation by cAMP produces two active catalytic monomers and a regulatory dimer that binds four cAMP molecules. Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.

Protein type: Protein kinase, regulatory subunit; Mitochondrial

Cellular Component: centrosome; membrane; cell soma; perinuclear region of cytoplasm; dendrite; mitochondrial inner membrane; cytoplasm; plasma membrane; dendritic spine; dendritic shaft; lipid raft; cAMP-dependent protein kinase complex

Molecular Function: protein domain specific binding; protein binding; ubiquitin protein ligase binding; cAMP-dependent protein kinase inhibitor activity; nucleotide binding; cAMP-dependent protein kinase regulator activity; cAMP binding; protein kinase binding

Biological Process: regulation of protein amino acid phosphorylation; learning; fatty acid metabolic process; regulation of protein kinase activity

Research Articles on Prkar2b

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Product Notes

The Prkar2b prkar2b (Catalog #AAA6006252) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PRKAR2B, ID (PRKAR2B, cAMP-dependent protein kinase type II-beta regulatory subunit) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PRKAR2B can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot, Immunohistochemistry. Dilution: ELISA: 1:1000 Western Blot: 1:500-1:1000 Immunohistochemistry (Paraffin): 10ug/ml. Researchers should empirically determine the suitability of the Prkar2b prkar2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRKAR2B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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