Rabbit Presenilin Enhancer 2 Polyclonal Antibody | anti-AT5G09310 antibody
Presenilin Enhancer 2, NT (Presenilin Enhancer Protein 2, Presenilin Enhancer 2 Homolog, PEN2, PEN-2, Gamma Secretase Subunit PEN2, Gamma Secretase Subunit PEN-2, MDS033, MSTP064, PSENEN)
Gene Names
AT5G09310; T5E8.110; T5E8_110
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
Presenilin Enhancer 2; Polyclonal Antibody; NT (Presenilin Enhancer Protein 2; Presenilin Enhancer 2 Homolog; PEN2; PEN-2; Gamma Secretase Subunit PEN2; Gamma Secretase Subunit PEN-2; MDS033; MSTP064; PSENEN); Anti -Presenilin Enhancer 2; anti-AT5G09310 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human PEN2. Species Crossreactivity: mouse, rat.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Applicable Applications for anti-AT5G09310 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Dilution: Western Blot: 0.5-1ug/ml
Dilution: Western Blot: 0.5-1ug/ml
Immunogen
13 amino acid peptide sequence near the amino terminus of human PEN2.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-AT5G09310 antibody
Presenilin enhancer protein 2 (PEN), a 12kD member of the PEN2 family and subunit of the gamma-secretase complex. This complex is an endoprotease that cleaves integral membrane proteins. These include Notch receptors and the beta-amyloid precursor protein which is cleaved to form amyloid beta peptide, a major component of the neuritic plaques found in Alzheimer's disease. The gamma secretase complex consists of nicastrin, the presenilin homodimers and APH1. It is the addition of PEN2, the final stage of gamma secretase maturation that facilitates endoproteolysis of presenilin and confers proteolytic activity. PEN2 expression has been observed in leukocytes, lung, placenta, small intestine, liver, kidney, spleen thymus, skeletal muscle, heart and brain.
Product Categories/Family for anti-AT5G09310 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
presenilin enhancer 2
NCBI Official Symbol
AT5G09310
NCBI Official Synonym Symbols
T5E8.110; T5E8_110
NCBI Protein Information
presenilin enhancer 2
UniProt Protein Name
Probable gamma-secretase subunit PEN-2
UniProt Entry Name
PEN2_ARATH
Uniprot Description
Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
Similar Products
Product Notes
The AT5G09310 (Catalog #AAA623045) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Presenilin Enhancer 2, NT (Presenilin Enhancer Protein 2, Presenilin Enhancer 2 Homolog, PEN2, PEN-2, Gamma Secretase Subunit PEN2, Gamma Secretase Subunit PEN-2, MDS033, MSTP064, PSENEN) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Presenilin Enhancer 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Dilution: Western Blot: 0.5-1ug/ml. Researchers should empirically determine the suitability of the AT5G09310 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Presenilin Enhancer 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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