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Rabbit anti-Human, Mouse Prefoldin subunit 1 Polyclonal Antibody | anti-PFDN1 antibody

Rabbit anti- human Prefoldin subunit 1 polyclonal Antibody, FITC conjugated

Gene Names
PFDN1; PDF; PFD1
Reactivity
Human, Mouse
Applications
ELISA
Purity
Caprylic Acid Ammonium Sulfate Precipitation Purified
Synonyms
Prefoldin subunit 1; Polyclonal Antibody; Rabbit anti- human Prefoldin subunit 1 polyclonal Antibody; FITC conjugated; anti-PFDN1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Sequence Length
122
Applicable Applications for anti-PFDN1 antibody
ELISA (EIA)
Storage Buffer
PBS
Conjugate
FITC
Immunogen
Recombinant human Prefoldin subunit 1 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-19832
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-PFDN1 antibody
PFDN1 is a heterohexameric chaperone protein which assists in the correct folding of other proteins. It binds specifically to cytosolic chaperonin and transfers target proteins. PFDN1 may function by selectively targeting nascent actin and tubulin chains pending their transfer to cytosolic chaperonin for final folding and/or assembly. It promotes folding in an environment in which there are many competing pathways for non native proteins.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
14,210 Da
NCBI Official Full Name
prefoldin subunit 1
NCBI Official Synonym Full Names
prefoldin subunit 1
NCBI Official Symbol
PFDN1
NCBI Official Synonym Symbols
PDF; PFD1
NCBI Protein Information
prefoldin subunit 1
UniProt Protein Name
Prefoldin subunit 1
Protein Family
UniProt Gene Name
PFDN1
UniProt Synonym Gene Names
PFD1
UniProt Entry Name
PFD1_HUMAN

NCBI Description

This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. [provided by RefSeq, Jul 2008]

Uniprot Description

PFDN1: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Belongs to the prefoldin subunit beta family.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: prefoldin complex

Molecular Function: transcription factor activity; unfolded protein binding

Biological Process: 'de novo' posttranslational protein folding; cell cycle; cellular protein metabolic process; protein folding; regulation of transcription, DNA-dependent

Research Articles on PFDN1

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Product Notes

The PFDN1 pfdn1 (Catalog #AAA715186) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti- human Prefoldin subunit 1 polyclonal Antibody, FITC conjugated reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Prefoldin subunit 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the PFDN1 pfdn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Prefoldin subunit 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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