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Testing Data (Gel: 12%SDS-PAGELane1: Hela cell lysateLane2:Mouse intestinum tenue tissue lysateLane3: 293T cell lysateLane4: 231 cell lysateLysates: 60 ug per lanePrimary antibody: 1/300 dilutionSecondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilutionExposure time: 1 second)

Rabbit anti-Human, Mouse PRDX6 Polyclonal Antibody | anti-PRDX6 antibody

PRDX6 Antibody

Gene Names
PRDX6; PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; HEL-S-128m
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Synonyms
PRDX6; Polyclonal Antibody; PRDX6 Antibody; peroxiredoxin 6; PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; anti-PRDX6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total PRDX6 protein.
Form/Format
Supplied at 0.8mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Sequence Length
1715
Applicable Applications for anti-PRDX6 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:1000-1:5000
Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100
Immunogen Type
Recombinant protein
Immunogen Description
Fusion protein corresponding to a region derived from 8-224 amino acids of human peroxiredoxin 6
Target Name
PRDX6
Preparation and Storage
Store at -20 degree C/1 year

Testing Data

(Gel: 12%SDS-PAGELane1: Hela cell lysateLane2:Mouse intestinum tenue tissue lysateLane3: 293T cell lysateLane4: 231 cell lysateLysates: 60 ug per lanePrimary antibody: 1/300 dilutionSecondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilutionExposure time: 1 second)

Testing Data (Gel: 12%SDS-PAGELane1: Hela cell lysateLane2:Mouse intestinum tenue tissue lysateLane3: 293T cell lysateLane4: 231 cell lysateLysates: 60 ug per lanePrimary antibody: 1/300 dilutionSecondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilutionExposure time: 1 second)

Immunohistochemistry (IHC)

(The image on the left is immunohistochemistry of paraffin-embedded human gastric cancer tissue using 31117 (PRDX6 Antibody) at dilution 1/25, on the right is treated with the fusion protein.)

Immunohistochemistry (IHC) (The image on the left is immunohistochemistry of paraffin-embedded human gastric cancer tissue using 31117 (PRDX6 Antibody) at dilution 1/25, on the right is treated with the fusion protein.)
Related Product Information for anti-PRDX6 antibody
The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
Product Categories/Family for anti-PRDX6 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
25,035 Da
NCBI Official Full Name
Homo sapiens peroxiredoxin 6, mRNA
NCBI Official Synonym Full Names
peroxiredoxin 6
NCBI Official Symbol
PRDX6
NCBI Official Synonym Symbols
PRX; p29; AOP2; 1-Cys; NSGPx; aiPLA2; HEL-S-128m
NCBI Protein Information
peroxiredoxin-6
UniProt Protein Name
Peroxiredoxin-6
Protein Family
UniProt Gene Name
PRDX6
UniProt Synonym Gene Names
AOP2; KIAA0106; 1-Cys PRX; aiPLA2; NSGPx
UniProt Entry Name
PRDX6_HUMAN

NCBI Description

The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]

Uniprot Description

PRDX6: Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. Belongs to the AhpC/TSA family. Rehydrin subfamily.

Protein type: Phospholipase; Oxidoreductase; Amino Acid Metabolism - phenylalanine; EC 1.11.1.15; EC 1.11.1.9; Energy Metabolism - methane

Chromosomal Location of Human Ortholog: 1q25.1

Cellular Component: cytoplasm; cytoplasmic membrane-bound vesicle; cytosol; extracellular space; lysosome; membrane

Molecular Function: antioxidant activity; glutathione peroxidase activity; peroxiredoxin activity; phospholipase A2 activity; protein binding; ubiquitin protein ligase binding

Biological Process: hydrogen peroxide catabolic process; phospholipid catabolic process; response to oxidative stress; response to reactive oxygen species

Research Articles on PRDX6

Similar Products

Product Notes

The PRDX6 prdx6 (Catalog #AAA9400778) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PRDX6 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PRDX6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:1000-1:5000 Western blotting: 1:500-1:2000 Immunohistochemistry: 1:25-1:100. Researchers should empirically determine the suitability of the PRDX6 prdx6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRDX6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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