Mouse IL-17 ELISA Kit | IL-17 elisa kit

IL-17 (Murine) OmniKine ELISA Kit

Cat. Num. AAA9501907

• Gene Names: Il17a; Il17; Ctla8; IL-17; Ctla-8; IL-17A
• Reactivity: Mouse
• Synonyms: IL-17; IL-17 (Murine) OmniKine ELISA Kit; Interleukin-17A; Cytotoxic T-lymphocyte-associated antigen 8; CTLA-8; IL-17 elisa kit

• Reactivity: Mouse
• Specificity: The OmniKine Murine IL-17 ELISA is capable of recognizing both recombinant and naturally produced Murine IL-17 proteins. The antigens listed below were tested at 50 ng/ml and exhibited less than 1% cross reactivity.; Human: IL-17A; The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.; Human: GM-CSF, IL-8, IL-17B, IL-17D, IL-17E, IL-17F; Murine: GM-CSF, IL-1beta, IL-3, IL-6, IL-7, IL-10, IL-15, IL-17F
• Form/Format: 12 x 8-Well Microstrips
• Sequence Length: 158

• Samples: Plasma, serum, lysate
• Assay Type: Sandwich ELISA
• Detection Range: 16-1000 pg/ml
• Sensitivity: 16-1000 pg/ml
• Detection Method: Colorimetric 450 nm
• Subtype: None
• Preparation and Storage: Store at 4 degree C for 6 months.

Testing Data

(The OmniKine Murine IL-17 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Murine IL-17 proteins within the range of 16-1000 pg/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 6754324
• NCBI GeneID: 16171
• NCBI Accession #: NP_034682.1
• NCBI GenBank Nucleotide #: NM_010552.3
• UniProt Accession #: Q62386; Q60971
• Molecular Weight: 17,490 Da
• NCBI Official Full Name: interleukin-17A
• NCBI Official Synonym Full Names: interleukin 17A
• NCBI Official Symbol: Il17a
• NCBI Official Synonym Symbols: Il17; Ctla8; IL-17; Ctla-8; IL-17A
• NCBI Protein Information: interleukin-17A
• UniProt Protein Name: Interleukin-17A
• UniProt Gene Name: Il17a
• UniProt Synonym Gene Names: Ctla8; Il17; IL-17; IL-17A; CTLA-8

NCBI Description

This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. The encoded protein plays a central role in host defense against diverse pathogens. The encoded protein is produced by activated T-cells and certain cell types of innate immune system. The active protein functions as either a homodimer with other interleukin-17 family members and signals through the interleukin-17 receptor to induce inflammatory cytokine production. Aberrant expression of this gene is associated with autoinflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Sep 2015]

Uniprot Description

IL17A: Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. Belongs to the IL-17 family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1|1 A4

Cellular Component: cytoplasm; external side of plasma membrane; extracellular region; extracellular space

Molecular Function: cytokine activity

Biological Process: defense response to fungus; inflammatory response; positive regulation of interleukin-23 production; positive regulation of osteoclast differentiation; positive regulation of transcription from RNA polymerase II promoter