Western Blot (WB)
(PRDM10 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the PRDM10 antibody detected the PRDM10 protein (arrow).)
Rabbit PRDM10 Polyclonal Antibody | anti-PRDM10 antibody
PRDM10 Antibody (Center)
Western Blot (WB)
(PRDM10 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the PRDM10 antibody detected the PRDM10 protein (arrow).)
Western Blot (WB)
(PRDM10 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the PRDM10 antibody detected the PRDM10 protein (arrow).)
that contains C2H2-type zinc-fingers. It also contains a positive
regulatory domain, which has been found in several other
zinc-finger transcription factors including those involved in B
cell differentiation and tumor suppression. Studies of the mouse
counterpart suggest that this protein may be involved in the
development of the central nerve system (CNS), as well as in the
pathogenesis of neuronal storage disease. Multiple alternatively
spliced transcript variants encoding distinct isoforms have been
observed.
Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Siegel, D.A., et al. Int. J. Dev. Neurosci. 20 (3-5), 373-389 (2002) :
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a transcription factor that contains C2H2-type zinc-fingers. It also contains a positive regulatory domain, which has been found in several other zinc-finger transcription factors including those involved in B cell differentiation and tumor suppression. Studies of the mouse counterpart suggest that this protein may be involved in the development of the central nerve system (CNS), as well as in the pathogenesis of neuronal storage disease. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Uniprot Description
PRDM10: May be involved in transcriptional regulation. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: C2H2-type zinc finger protein; Methyltransferase, protein lysine, predicted; Transcription regulation
Chromosomal Location of Human Ortholog: 11q25
Cellular Component: nucleus
Molecular Function: methyltransferase activity; DNA binding; metal ion binding
Biological Process: methylation; transcription, DNA-dependent; regulation of transcription, DNA-dependent
Research Articles on PRDM10
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Product Notes
The PRDM10 prdm10 (Catalog #AAA9204351) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 744-772. The PRDM10 Antibody (Center) reacts with Human, mouse (Predicted Reactivity: Zebrafish) and may cross-react with other species as described in the data sheet. AAA Biotech's PRDM10 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the PRDM10 prdm10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PRDM10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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