Rabbit PPP2R2C Polyclonal Antibody | anti-PPP2R2C antibody

PPP2R2C Antibody

Cat. Num. AAA9630864

• Gene Names: PPP2R2C; PR52; PR55G; IMYPNO; IMYPNO1; MGC33570; B55-GAMMA
• Reactivity: Human, Mouse, Rat
• Applications: ELISA
• Purity: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
• Synonyms: PPP2R2C; Polyclonal Antibody; PPP2R2C Antibody; 2ABG_HUMAN; B55 gamma; Gamma isoform of regulatory subunit B55 protein phosphatase 2; IMYPNO 1; IMYPNO; IMYPNO1; MGC33570; OTTHUMP00000115505; Phosphoprotein phosphatase 2A BR gamma regulatory chain; PP2A subunit B B gamma isoform; PP2A subunit B B55 gamma isoform; PP2A subunit B isoform B55-gamma; PP2A subunit B isoform gamma; PP2A subunit B isoform PR55-gamma; PP2A subunit B isoform R2-gamma; PP2A subunit B PR55 gamma isoform; PP2A subunit B R2 gamma isoform; PPP2R2C protein; PR 52; PR 55G; PR52; PR55G; Protein phosphatase 2 (formerly 2A) regulatory subunit B gamma isoform; Protein phosphatase 2 regulatory subunit B gamma; Protein phosphatase 2 regulatory subunit B gamma isoform; Protein phosphatase 2A1 B gamma subunit; Serine/threonine protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform; anti-PPP2R2C antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Specificity: PPP2R2C Antibody detects endogenous levels of PPP2R2C.
• Purity/Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
• Form/Format: Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1mg/ml (varies by lot)

• Applicable Applications for anti-PPP2R2C antibody: ELISA (EIA)(peptide)
• Application Notes: ELISA(peptide): 1:20000-1:40000
• Immunogen: A synthesized peptide derived from human PPP2R2C.
• Conjugation: Unconjugated
• Similarity: Belongs to the phosphatase 2A regulatory subunit B family.
• Subunit Structure: PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules (By similarity). Interacts with IER5.
• Function: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
• Preparation and Storage: Store at -20 degree C. Stable for 12 months from date of receipt.

Product Categories/Family for anti-PPP2R2C antibody

Primary

NCBI and Uniprot Product Information

• NCBI GI #: 32967593
• NCBI GeneID: 5522
• NCBI Accession #: NP_870991.1
• NCBI GenBank Nucleotide #: NM_181876.2
• UniProt Accession #: Q9Y2T4; Q7Z4V7; Q8NEC4; Q9H3G7; A8MSY7; Q59GC6
• Molecular Weight: 51,515 Da
• NCBI Official Full Name: protein phosphatase 2, regulatory subunit B, gamma isoform b
• NCBI Official Synonym Full Names: protein phosphatase 2, regulatory subunit B, gamma
• NCBI Official Symbol: PPP2R2C
• NCBI Official Synonym Symbols: PR52; PR55G; IMYPNO; IMYPNO1; MGC33570; B55-GAMMA
• NCBI Protein Information: protein phosphatase 2, regulatory subunit B, gamma; OTTHUMP00000115505; OTTHUMP00000115506; OTTHUMP00000217568; OTTHUMP00000217634; OTTHUMP00000217635; PP2A, subunit B, B-gamma isoform; PP2A, subunit B, R2-gamma isoform; PP2A, subunit B, B55-gamma isoform
• UniProt Protein Name: Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform
• Protein Family: Serine/threonine-protein phosphatase
• UniProt Gene Name: PPP2R2C
• UniProt Entry Name: 2ABG_HUMAN

NCBI Description

The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Uniprot Description

PPP2R2C: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Belongs to the phosphatase 2A regulatory subunit B family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein phosphatase, regulatory subunit

Chromosomal Location of Human Ortholog: 4p16.1

Cellular Component: protein phosphatase type 2A complex

Molecular Function: protein binding; protein phosphatase type 2A regulator activity

Biological Process: regulation of catalytic activity; signal transduction