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Western Blot (WB) (PPP2CB Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the PPP2CB antibody detected the PPP2CB protein (arrow).)

Rabbit anti-Human PPP2CB Polyclonal Antibody | anti-PPP2CB antibody

PPP2CB, CT (PPP2CB, Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform) (APC)

Gene Names
PPP2CB; PP2CB; PP2Abeta
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
PPP2CB; Polyclonal Antibody; CT (PPP2CB; Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform) (APC); Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; anti-PPP2CB antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-PPP2CB antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
PPP2CB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-307 amino acids from the C-terminal region of human PPP2CB.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(PPP2CB Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the PPP2CB antibody detected the PPP2CB protein (arrow).)

Western Blot (WB) (PPP2CB Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the PPP2CB antibody detected the PPP2CB protein (arrow).)

Immunohistochemistry (IHC)

(PPP2CB Antibody (C-term) (AP13765b)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PPP2CB Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (PPP2CB Antibody (C-term) (AP13765b)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PPP2CB Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-PPP2CB antibody
PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
Product Categories/Family for anti-PPP2CB antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36
NCBI Official Full Name
serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
NCBI Official Synonym Full Names
protein phosphatase 2 catalytic subunit beta
NCBI Official Symbol
PPP2CB
NCBI Official Synonym Symbols
PP2CB; PP2Abeta
NCBI Protein Information
serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
UniProt Protein Name
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform
UniProt Gene Name
PPP2CB
UniProt Synonym Gene Names
PP2A-beta
UniProt Entry Name
PP2AB_HUMAN

NCBI Description

This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. [provided by RefSeq, Mar 2010]

Uniprot Description

PPP2CB: one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits.

Protein type: Protein phosphatase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis; EC 3.1.3.16

Chromosomal Location of Human Ortholog: 8p12

Cellular Component: spindle pole; protein phosphatase type 2A complex; nucleus; cytosol; chromosome, pericentric region

Molecular Function: protein C-terminus binding; protein binding; metal ion binding; protein serine/threonine phosphatase activity

Biological Process: response to antibiotic; proteasomal ubiquitin-dependent protein catabolic process; apoptotic mitochondrial changes; fibroblast growth factor receptor signaling pathway; response to hydrogen peroxide; regulation of gene expression; negative regulation of Ras protein signal transduction; protein amino acid dephosphorylation

Research Articles on PPP2CB

Similar Products

Product Notes

The PPP2CB ppp2cb (Catalog #AAA6336633) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPP2CB, CT (PPP2CB, Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform) (APC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PPP2CB can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:10-50 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PPP2CB ppp2cb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPP2CB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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