Rabbit PPP2CB Polyclonal Antibody | anti-PPP2CB antibody
PPP2CB Antibody
WB: 1:1000-1:5000
IHC: 1:50-1:200
Immunohistochemistry (IHC)-Paraffin
(The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using MBS7128115(PPP2CB Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200))
SDS-Page
(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane: Jurkat cells, Primary antibody: MBS7128115(PPP2CB Antibody) at dilution 1/1200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. [provided by RefSeq, Mar 2010]
Uniprot Description
PPP2CB: one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits.
Protein type: Protein phosphatase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis; EC 3.1.3.16
Chromosomal Location of Human Ortholog: 8p12
Cellular Component: spindle pole; protein phosphatase type 2A complex; nucleus; cytosol; chromosome, pericentric region
Molecular Function: protein C-terminus binding; protein binding; metal ion binding; protein serine/threonine phosphatase activity
Biological Process: response to antibiotic; proteasomal ubiquitin-dependent protein catabolic process; apoptotic mitochondrial changes; fibroblast growth factor receptor signaling pathway; response to hydrogen peroxide; regulation of gene expression; negative regulation of Ras protein signal transduction; protein amino acid dephosphorylation
Research Articles on PPP2CB
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Product Notes
The PPP2CB ppp2cb (Catalog #AAA7128115) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPP2CB Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PPP2CB can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:2000-1:10000 WB: 1:1000-1:5000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the PPP2CB ppp2cb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPP2CB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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