Western Blot (WB)
(Western blot analysis of PPP1R1C using HeLa whole cell lysates)
Rabbit anti-Human, Mouse PPP1R1C Polyclonal Antibody | anti-PPP1R1C antibody
PPP1R1C Antibody
Gene Names
PPP1R1C; IPP5
Reactivity
Human, Mouse
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
PPP1R1C; Polyclonal Antibody; PPP1R1C Antibody; Inhibitor 5 of protein phosphatase 1; IPP5; PP1 inhibitor protein 5; Ppp1r1c; PPR1C_HUMAN; Protein phosphatase 1 regulatory subunit 1A; Protein phosphatase 1 regulatory subunit 1C; protein phosphatase 1; regulatory (inhibitor) subunit 1C; anti-PPP1R1C antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
PPP1R1C antibody detects endogenous levels of total PPP1R1C
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
109
Applicable Applications for anti-PPP1R1C antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human PPP1R1C
Tissue Specificity
Expressed in heart, skeletal muscle, liver and testis (at protein level).
Predicted Cross Reactivity
Pig, Zebrafish, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus
Similarity
Pig (100%), Zebrafish (89%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (89%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of PPP1R1C using HeLa whole cell lysates)
Western Blot (WB)
(Western blot analysis of PPP1R1C using HeLa whole cell lysates)
Related Product Information for anti-PPP1R1C antibody
Function: Inhibitor of protein-phosphatase 1. Promotes cell growth and cell cycle progress at the G1/S transition. May increase cell susceptibility to TNF-induced apoptosis.
Subunit Structure: Interacts with PPP1CB.
Post-translational Modifications: Phosphorylation of Thr-34 is required for activity.
Similarity: Belongs to the protein phosphatase inhibitor 1 family.
Subunit Structure: Interacts with PPP1CB.
Post-translational Modifications: Phosphorylation of Thr-34 is required for activity.
Similarity: Belongs to the protein phosphatase inhibitor 1 family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 12 kDa
Predicted: 13 kDa
Predicted: 13 kDa
NCBI Official Full Name
protein phosphatase 1 regulatory subunit 1C isoform 2
NCBI Official Synonym Full Names
protein phosphatase 1 regulatory inhibitor subunit 1C
NCBI Official Symbol
PPP1R1C
NCBI Official Synonym Symbols
IPP5
NCBI Protein Information
protein phosphatase 1 regulatory subunit 1C
UniProt Protein Name
Protein phosphatase 1 regulatory subunit 1C
Protein Family
UniProt Gene Name
PPP1R1C
UniProt Synonym Gene Names
IPP5
NCBI Description
Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al., 2008 [PubMed 18310074]).[supplied by OMIM, Feb 2010]
Uniprot Description
Inhibitor of protein-phosphatase 1. Promotes cell growth and cell cycle progress at the G1/S transition. May increase cell susceptibility to TNF-induced apoptosis.
Research Articles on PPP1R1C
Similar Products
Product Notes
The PPP1R1C ppp1r1c (Catalog #AAA9610096) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPP1R1C Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PPP1R1C can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the PPP1R1C ppp1r1c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPP1R1C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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