Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using PPM1M Polyclonal Antibody at dilution of 1:100(×200))
Rabbit anti-Human, Mouse PPM1M Polyclonal Antibody | anti-PPM1M antibody
PPM1M Polyclonal Antibody
Gene Names
PPM1M; PP2CE; PP2Ceta; PP2C-eta
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
PPM1M; Polyclonal Antibody; PPM1M Polyclonal Antibody; FLJ32332; PP2C eta; PP2C-eta; PP2CE; PP2Ceta; Protein phosphatase 1M (PP2C domain containing); Protein phosphatase 1M; Protein phosphatase 2C isoform eta; anti-PPM1M antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
1.74mg/mL (varies by lot)
Sequence Length
247
Applicable Applications for anti-PPM1M antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:100-1:300
ELISA: 1:5000-1:10000
ELISA: 1:5000-1:10000
Immunogen
Fusion protein of human PPM1M
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using PPM1M Polyclonal Antibody at dilution of 1:100(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using PPM1M Polyclonal Antibody at dilution of 1:100(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human tonsil tissue using PPM1M Polyclonal Antibody at dilution of 1:100(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human tonsil tissue using PPM1M Polyclonal Antibody at dilution of 1:100(×200))
Related Product Information for anti-PPM1M antibody
PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX). PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42).
Product Categories/Family for anti-PPM1M antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
protein phosphatase 1M isoform b
NCBI Official Synonym Full Names
protein phosphatase, Mg2+/Mn2+ dependent 1M
NCBI Official Symbol
PPM1M
NCBI Official Synonym Symbols
PP2CE; PP2Ceta; PP2C-eta
NCBI Protein Information
protein phosphatase 1M
UniProt Protein Name
Protein phosphatase 1M
Protein Family
UniProt Gene Name
PPM1M
UniProt Synonym Gene Names
PPM1E; PP2C-eta; PP2CE
UniProt Entry Name
PPM1M_HUMAN
Research Articles on PPM1M
1. PP2Ceta-2 inhibits the IL-1-NF-kappaB signalling pathway by selectively dephosphorylating IKKbeta.
Similar Products
Product Notes
The PPM1M ppm1m (Catalog #AAA2561079) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPM1M Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PPM1M can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:100-1:300 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the PPM1M ppm1m for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPM1M, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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