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Western Blot (WB) (PPIL2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PPIL2 antibody detected the PPIL2 protein (arrow).)

Rabbit anti-Human PPIL2 Polyclonal Antibody | anti-PPIL2 antibody

PPIL2, CT (PPIL2, Peptidyl-prolyl cis-trans isomerase-like 2, Cyclophilin-60, Cyclophilin-like protein Cyp-60, Rotamase PPIL2) (AP)

Gene Names
PPIL2; CYC4; CYP60; UBOX7; Cyp-60; hCyP-60
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
PPIL2; Polyclonal Antibody; CT (PPIL2; Peptidyl-prolyl cis-trans isomerase-like 2; Cyclophilin-60; Cyclophilin-like protein Cyp-60; Rotamase PPIL2) (AP); Rotamase PPIL2; anti-PPIL2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Applicable Applications for anti-PPIL2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
PPIL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-431 amino acids from the C-terminal region of human PPIL2.
Conjugate
AP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(PPIL2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PPIL2 antibody detected the PPIL2 protein (arrow).)

Western Blot (WB) (PPIL2 Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PPIL2 antibody detected the PPIL2 protein (arrow).)
Related Product Information for anti-PPIL2 antibody
This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. This protein interacts with the proteinase inhibitor eglin c and is localized in the nucleus. Multiple transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-PPIL2 antibody
References
Carson, R., et al. Neuromolecular Med. 11(4):337-344(2009). Pushkarsky, T., et al. J. Biol. Chem. 280(30):27866-27871(2005). Hatakeyama, S., et al. J. Biol. Chem. 276(35):33111-33120(2001). Wang, B.B., et al. Biochem. J. 314 (PT 1), 313-319 (1996).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
59,458 Da
NCBI Official Full Name
peptidyl-prolyl cis-trans isomerase-like 2 isoform a
NCBI Official Synonym Full Names
peptidylprolyl isomerase (cyclophilin)-like 2
NCBI Official Symbol
PPIL2
NCBI Official Synonym Symbols
CYC4; CYP60; UBOX7; Cyp-60; hCyP-60
NCBI Protein Information
peptidyl-prolyl cis-trans isomerase-like 2; PPIase; U-box domain containing 7; cyclophilin, 60kDa; cyclophilin-60; cyclophilin-like protein CyP-60; peptidylprolyl cis-trans isomerase; rotamase PPIL2
UniProt Protein Name
Peptidyl-prolyl cis-trans isomerase-like 2
UniProt Gene Name
PPIL2
UniProt Synonym Gene Names
PPIaseCurated
UniProt Entry Name
PPIL2_HUMAN

NCBI Description

This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. This protein interacts with the proteinase inhibitor eglin c and is localized in the nucleus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

PPIL2: a peptidylprolyl isomerase (PPIase) of the cyclophilin-type family. PPIases accelerate the folding of proteins by catalyzing the cis-trans isomerization of proline imidic peptide bonds. Two alternatively-spliced isoforms have been described.

Protein type: Ligase; Cyclophilin; Ubiquitin conjugating system; EC 5.2.1.8; Spliceosome; Ubiquitin ligase; Isomerase

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: nucleoplasm; Golgi lumen; cytoplasm; plasma membrane; nucleus

Molecular Function: protein binding; peptidyl-prolyl cis-trans isomerase activity; ligase activity

Biological Process: protein polyubiquitination; protein peptidyl-prolyl isomerization; protein folding; blood coagulation; leukocyte migration

Research Articles on PPIL2

Similar Products

Product Notes

The PPIL2 ppil2 (Catalog #AAA6336302) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPIL2, CT (PPIL2, Peptidyl-prolyl cis-trans isomerase-like 2, Cyclophilin-60, Cyclophilin-like protein Cyp-60, Rotamase PPIL2) (AP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PPIL2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:100-500 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PPIL2 ppil2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPIL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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