Western Blot (WB)
(POU2F2 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the POU2F2 antibody detected the POU2F2 protein (arrow).)
Rabbit POU2F2 Polyclonal Antibody | anti-POU2F2 antibody
POU2F2 Antibody (N-term)
Western Blot (WB)
(POU2F2 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the POU2F2 antibody detected the POU2F2 protein (arrow).)
Western Blot (WB)
(POU2F2 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the POU2F2 antibody detected the POU2F2 protein (arrow).)
Immunohistochemistry (IHC)
(POU2F2 Antibody (N-term) (MBS9215104)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of POU2F2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(POU2F2 Antibody (N-term) (MBS9215104)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of POU2F2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Bailey, S.D., et al. Diabetes Care (2010) In press :
Advani, A.S., et al. Leuk. Lymphoma 51(4):606-612(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Filipski, K.K., et al. Clin. Pharmacol. Ther. 86(4):396-402(2009)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Uniprot Description
Oct2: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. Belongs to the POU transcription factor family. Class- 2 subfamily. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: cytoplasm; nucleus
Molecular Function: protein domain specific binding; sequence-specific DNA binding; transcription factor activity
Biological Process: immunoglobulin secretion during immune response; transcription from RNA polymerase II promoter; mature B cell differentiation; positive regulation of transcription, DNA-dependent; cell maturation; humoral immune response
Research Articles on POU2F2
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Product Notes
The POU2F2 pou2f2 (Catalog #AAA9215104) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 10-39. The POU2F2 Antibody (N-term) reacts with Human (Predicted Reactivity: Mouse, Pig) and may cross-react with other species as described in the data sheet. AAA Biotech's POU2F2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the POU2F2 pou2f2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "POU2F2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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