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Rabbit POM121 Polyclonal Antibody | anti-POM121 antibody

POM121 Conjugated Antibody

Gene Names
POM121; P145; POM121A
Reactivity
Human, Mouse, Rat
Applications
Most Applications
Synonyms
POM121; Polyclonal Antibody; POM121 Conjugated Antibody; Nuclear envelope pore membrane protein POM 121; Pore membrane protein of 121 kDa; P145; anti-POM121 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
POM121 antibody detects endogenous levels of total POM121
Form/Format
0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
Applicable Applications for anti-POM121 antibody
Most Applications
Application Notes
Suggested Dilution:
AF350 conjugated: most applications: 1:50-1:250
AF405 conjugated: most applications: 1:50-1:250
AF488 conjugated: most applications: 1:50-1:250
AF555 conjugated: most applications: 1:50-1:250
AF594 conjugated: most applications: 1:50-1:250
AF647 conjugated: most applications: 1:50-1:250
AF680 conjugated: most applications: 1:50-1:250
AF750 conjugated: most applications: 1:50-1:250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000
Immunogen
A synthesized peptide derived from human POM121
Conjugation
Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750
Excitation Emission
AF350: 346nm/442nm
Preparation and Storage
Store at 4 degree C for 6 months.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
100,864 Da
NCBI Official Full Name
nuclear envelope pore membrane protein POM 121 isoform 2
NCBI Official Synonym Full Names
POM121 transmembrane nucleoporin
NCBI Official Symbol
POM121
NCBI Official Synonym Symbols
P145; POM121A
NCBI Protein Information
nuclear envelope pore membrane protein POM 121; nucleoporin Nup121; POM121 membrane glycoprotein; nuclear pore membrane protein 121 kDa; nuclear envelope pore membrane protein POM 121A
UniProt Protein Name
Nuclear envelope pore membrane protein POM 121
Protein Family
UniProt Gene Name
POM121
UniProt Synonym Gene Names
KIAA0618; NUP121; POM121A
UniProt Entry Name
P121A_HUMAN

NCBI Description

This gene encodes a transmembrane protein that localizes to the inner nuclear membrane and forms a core component of the nuclear pore complex, which mediates transport to and from the nucleus. The encoded protein may anchor this complex to the nuclear envelope. There are multiple related genes and pseudogenes for this gene on chromosomes 5, 7, 15, and 22. Alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2013]

Uniprot Description

POM121: a single-pass membrane protein that is an essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL). Stably associated with the NPC throughout interphase and with the endoplasmic reticulum during metaphase. Contains F-X-F-G repeats. Belongs to the POM121 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Nucleoporin

Chromosomal Location of Human Ortholog: 7q11.23

Cellular Component: endoplasmic reticulum membrane; nuclear membrane; nuclear envelope; nuclear pore

Biological Process: mRNA transport; viral reproduction; cytokine and chemokine mediated signaling pathway; mitotic nuclear envelope disassembly; pathogenesis; glucose transport; viral infectious cycle; protein transport; hexose transport; carbohydrate metabolic process; gene expression; viral transcription; mitotic cell cycle; transmembrane transport

Research Articles on POM121

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Product Notes

The POM121 pom121 (Catalog #AAA9453406) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The POM121 Conjugated Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's POM121 can be used in a range of immunoassay formats including, but not limited to, Most Applications. Suggested Dilution: AF350 conjugated: most applications: 1:50-1:250 AF405 conjugated: most applications: 1:50-1:250 AF488 conjugated: most applications: 1:50-1:250 AF555 conjugated: most applications: 1:50-1:250 AF594 conjugated: most applications: 1:50-1:250 AF647 conjugated: most applications: 1:50-1:250 AF680 conjugated: most applications: 1:50-1:250 AF750 conjugated: most applications: 1:50-1:250 Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1:50-1:1000. Researchers should empirically determine the suitability of the POM121 pom121 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "POM121, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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