Rabbit anti-Human POM121 Polyclonal Antibody | anti-POM121 antibody

POM121 Polyclonal Antibody

Cat. Num. AAA2560765

• Gene Names: POM121; P145; POM121A
• Reactivity: Human
• Applications: Immunohistochemistry, ELISA
• Purity: Antigen Affinity Purification
• Synonyms: POM121; Polyclonal Antibody; POM121 Polyclonal Antibody; DKFZp586G1822; DKFZp586P2220; FLJ41820; KIAA0618; MGC3792; Nuclear envelope pore membrane protein POM 121; Nuclear envelope pore membrane protein POM 121A; Nuclear pore membrane protein 121 kDa; Nucleoporin Nup121; NUP121; P121A; P145; Pom121; POM121 membrane glycoprotein; POM121A; Pore membrane protein of 121 kDa; anti-POM121 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Form/Format: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
• Concentration: 1.32mg/mL (varies by lot)
• Sequence Length: 984

• Applicable Applications for anti-POM121 antibody: Immunohistochemistry (IHC), ELISA (EIA)
• Application Notes: IHC: 1:50-1:300; ELISA: 1:5000-1:10000
• Immunogen: Fusion protein of human POM121
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using POM121 Polyclonal Antibody at dilution of 1:75(×200))

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using POM121 Polyclonal Antibody at dilution of 1:75(×200))

Related Product Information for anti-POM121 antibody

This gene encodes a transmembrane protein that localizes to the inner nuclear membrane and forms a core component of the nuclear pore complex, which mediates transport to and from the nucleus. The encoded protein may anchor this complex to the nuclear envelope. There are multiple related genes and pseudogenes for this gene on chromosomes 5, 7, 15, and 22. Alternatively spliced transcript variants encoding different isoforms have been observed.

NCBI and Uniprot Product Information

• NCBI GI #: 26051278
• NCBI GeneID: 9883
• NCBI Accession #: NP_742017.1; BC008794
• NCBI GenBank Nucleotide #: NP_742017.1
• UniProt Accession #: Q96HA1
• NCBI Official Full Name: nuclear envelope pore membrane protein POM 121 isoform 2
• NCBI Official Synonym Full Names: POM121 transmembrane nucleoporin
• NCBI Official Symbol: POM121
• NCBI Official Synonym Symbols: P145; POM121A
• NCBI Protein Information: nuclear envelope pore membrane protein POM 121
• UniProt Protein Name: Nuclear envelope pore membrane protein POM 121
• Protein Family: POM121-like protein
• UniProt Gene Name: POM121
• UniProt Synonym Gene Names: KIAA0618; NUP121; POM121A
• UniProt Entry Name: P121A_HUMAN

NCBI Description

This gene encodes a transmembrane protein that localizes to the inner nuclear membrane and forms a core component of the nuclear pore complex, which mediates transport to and from the nucleus. The encoded protein may anchor this complex to the nuclear envelope. There are multiple related genes and pseudogenes for this gene on chromosomes 5, 7, 15, and 22. Alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2013]

Uniprot Description

POM121: a single-pass membrane protein that is an essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL). Stably associated with the NPC throughout interphase and with the endoplasmic reticulum during metaphase. Contains F-X-F-G repeats. Belongs to the POM121 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Nucleoporin

Chromosomal Location of Human Ortholog: 7q11.23

Cellular Component: endoplasmic reticulum membrane; nuclear membrane; nuclear envelope; nuclear pore

Biological Process: mRNA transport; viral reproduction; cytokine and chemokine mediated signaling pathway; mitotic nuclear envelope disassembly; pathogenesis; glucose transport; viral infectious cycle; protein transport; hexose transport; carbohydrate metabolic process; gene expression; viral transcription; mitotic cell cycle; transmembrane transport