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Western Blot (WB) (Western Blot: Sample: Recombinant PARP4, Human.)

Rabbit anti-Human Poly ADP Ribose Polymerase 4 Polyclonal Antibody | anti-PARP4 antibody

Polyclonal Antibody to Poly ADP Ribose Polymerase 4 (PARP4)

Gene Names
PARP4; PH5P; p193; ARTD4; PARPL; VPARP; VWA5C; PARP-4; VAULT3; ADPRTL1
Reactivity
Human
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry, ELISA
Purity
Affinity Chromatography
Synonyms
Poly ADP Ribose Polymerase 4; Polyclonal Antibody; Polyclonal Antibody to Poly ADP Ribose Polymerase 4 (PARP4); anti-PARP4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody is a rabbit polyclonal antibody raised against PARP4. It has beenselected for its ability to recognize PARP4 in immunohistochemical staining andwestern blotting.
Purity/Purification
Affinity Chromatography
Form/Format
Liquid
Concentration
500ug/mL (varies by lot)
Applicable Applications for anti-PARP4 antibody
Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)
Application Notes
Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.
Fragment
PARP4 (Val338~Thr609)
Organism Species
Homo sapiens (Human)
Cross Reactivity
Human
Conjugate
No Conjugate
Immunogen
Recombinant PARP4 (Val338~Thr609) expressed in E Coli.
Conjugated Antibody
The APC conjugated antibody version of this item is also available as catalog #MBS2069302
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Western Blot (WB)

(Western Blot: Sample: Recombinant PARP4, Human.)

Western Blot (WB) (Western Blot: Sample: Recombinant PARP4, Human.)

Immunohistochemistry (IHC)

(DABstainingonIHC-P.Samples:HumanTissue))

Immunohistochemistry (IHC) (DABstainingonIHC-P.Samples:HumanTissue))

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
143
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
192,595 Da
NCBI Official Full Name
poly
NCBI Official Synonym Full Names
poly(ADP-ribose) polymerase family member 4
NCBI Official Symbol
PARP4
NCBI Official Synonym Symbols
PH5P; p193; ARTD4; PARPL; VPARP; VWA5C; PARP-4; VAULT3; ADPRTL1
NCBI Protein Information
poly [ADP-ribose] polymerase 4
UniProt Protein Name
Poly [ADP-ribose] polymerase 4
UniProt Gene Name
PARP4
UniProt Synonym Gene Names
ADPRTL1; KIAA0177; PARPL; PARP-4; ARTD4; PH5P; VPARP

NCBI Description

This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus. [provided by RefSeq, Jul 2008]

Uniprot Description

PARP4: Component of the vault ribonucleoprotein particle, at least composed of MVP, PARP4 and one or more vault RNAs (vRNAs). Binds to MVP. Associates with TEP1.

Protein type: EC 2.4.2.30; Transferase

Chromosomal Location of Human Ortholog: 13q12.12

Cellular Component: cytoplasm; cytosol; extracellular exosome; intracellular ribonucleoprotein complex; membrane; nucleus; spindle microtubule

Molecular Function: DNA binding; enzyme binding; NAD+ ADP-ribosyltransferase activity; protein binding

Biological Process: cell death; cellular protein modification process; cellular response to DNA damage stimulus; DNA repair; inflammatory response; protein ADP-ribosylation; regulation of telomerase activity; response to drug

Research Articles on PARP4

Similar Products

Product Notes

The PARP4 parp4 (Catalog #AAA2026636) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Poly ADP Ribose Polymerase 4 (PARP4) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Poly ADP Ribose Polymerase 4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/mL Immunohistochemistry: 5-20ug/mL Immunocytochemistry: 5-20ug/mL Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the PARP4 parp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Poly ADP Ribose Polymerase 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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