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Western Blot (WB) (Western blot analysis of POLR2G expression in MCF7 (A), A549 (B), mouse brain (C), rat brain (D) whole cell lysates.)

Rabbit POLR2G Polyclonal Antibody | anti-POLR2G antibody

Anti-POLR2G Antibody

Gene Names
POLR2G; RPB7; RPB19; hRPB19; hsRPB7
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Purified by immunogen affinity chromatography
Synonyms
POLR2G; Polyclonal Antibody; Anti-POLR2G Antibody; RPB7; DNA-directed RNA polymerase II subunit RPB7; RNA polymerase II subunit B7; DNA-directed RNA polymerase II subunit G; RNA polymerase II 19 kDa subunit; RPB19; anti-POLR2G antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of POLR2G protein.
Purity/Purification
Purified by immunogen affinity chromatography
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Sequence Length
172
Applicable Applications for anti-POLR2G antibody
Western Blot (WB)
Application Notes
WB: 1/500 - 1/2000
Immunogen
Recombinant full length protein of human POLR2G
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of POLR2G expression in MCF7 (A), A549 (B), mouse brain (C), rat brain (D) whole cell lysates.)

Western Blot (WB) (Western blot analysis of POLR2G expression in MCF7 (A), A549 (B), mouse brain (C), rat brain (D) whole cell lysates.)
Related Product Information for anti-POLR2G antibody
Rabbit polyclonal antibody to POLR2G

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
19,294 Da
NCBI Official Full Name
DNA-directed RNA polymerase II subunit RPB7
NCBI Official Synonym Full Names
RNA polymerase II subunit G
NCBI Official Symbol
POLR2G
NCBI Official Synonym Symbols
RPB7; RPB19; hRPB19; hsRPB7
NCBI Protein Information
DNA-directed RNA polymerase II subunit RPB7
UniProt Protein Name
DNA-directed RNA polymerase II subunit RPB7
UniProt Gene Name
POLR2G
UniProt Synonym Gene Names
RPB7; RNA polymerase II subunit B7; RPB19

NCBI Description

This gene encodes the seventh largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The protein functions in transcription initiation, and is also thought to help stabilize transcribing polyermase molecules during elongation. [provided by RefSeq, Jan 2009]

Uniprot Description

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (). Binds RNA.

Research Articles on POLR2G

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Product Notes

The POLR2G polr2g (Catalog #AAA8292345) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-POLR2G Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's POLR2G can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1/500 - 1/2000. Researchers should empirically determine the suitability of the POLR2G polr2g for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "POLR2G, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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