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Testing Data

Rabbit PNPLA6 Polyclonal Antibody | anti-PNPLA6 antibody

PNPLA6 Antibody

Gene Names
PNPLA6; NTE; sws; BNHS; LNMS; OMCS; SPG39; NTEMND; iPLA2delta
Reactivity
Human, Mouse
Predicted: Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Synonyms
PNPLA6; Polyclonal Antibody; PNPLA6 Antibody; anti-PNPLA6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Predicted: Rat
Clonality
Polyclonal
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3
Sequence Length
4452
Applicable Applications for anti-PNPLA6 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20,000-1:80,000
WB: 1:1,000-1:2,000
IHC: 1:100-1:500
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.

Testing Data

Testing Data

Testing Data

Testing Data
Related Product Information for anti-PNPLA6 antibody
Rabbit polyclonal PNPLA6 (1) antibody was raised against a recombinate human PNPLA6 protein 324-516aa (BC051768).
References
(1) Hein, N.D., Rainier, S.R., Richardson, R.J. et al. Motor neuron disease due to neuropathy target esterase mutation: enzyme analysis of fibroblasts from human subjects yields insights into pathogenesis. Toxicol. Lett. 199 (1), 1-5 (2010).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
143,351 Da
NCBI Official Full Name
Homo sapiens patatin-like phospholipase domain containing 6, mRNA
NCBI Official Synonym Full Names
patatin like phospholipase domain containing 6
NCBI Official Symbol
PNPLA6
NCBI Official Synonym Symbols
NTE; sws; BNHS; LNMS; OMCS; SPG39; NTEMND; iPLA2delta
NCBI Protein Information
neuropathy target esterase
UniProt Protein Name
Neuropathy target esterase
UniProt Gene Name
PNPLA6
UniProt Synonym Gene Names
NTE

NCBI Description

This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Uniprot Description

Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy.

Research Articles on PNPLA6

Similar Products

Product Notes

The PNPLA6 pnpla6 (Catalog #AAA859858) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PNPLA6 Antibody reacts with Human, Mouse Predicted: Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PNPLA6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20,000-1:80,000 WB: 1:1,000-1:2,000 IHC: 1:100-1:500. Researchers should empirically determine the suitability of the PNPLA6 pnpla6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PNPLA6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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