Western Blot (WB)
(PMF1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PMF1 antibody detected the PMF1 protein (arrow).)
Rabbit anti-Human PMF1 Polyclonal Antibody | anti-PMF1 antibody
PMF1 Antibody (Center)
Western Blot (WB)
(PMF1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PMF1 antibody detected the PMF1 protein (arrow).)
Western Blot (WB)
(PMF1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PMF1 antibody detected the PMF1 protein (arrow).)
Kline, S.L., et al. J. Cell Biol. 173(1):9-17(2006)
Obuse, C., et al. Nat. Cell Biol. 6(11):1135-1141(2004)
Wang, Y., et al. Biochem. J. 366 (PT 1), 79-86 (2002) :
Wang, Y., et al. Biochem. J. 355 (PT 1), 45-49 (2001) :
NCBI and Uniprot Product Information
Uniprot Description
PMF1: Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT. Six isoforms of the human protein are produced by alternative splicing. Induced by polyamine analogs in analog-sensitive H157 cells. Component of the MIS12 complex composed of MIS12, DSN1, NSL1 and PMF1. Interacts with COPS7A. Interacts via its coiled- coil domain with the leucine-zipper domain of NFE2L2. The interaction with NFE2L2 is required for the transcriptional regulation of SSAT.
Chromosomal Location of Human Ortholog: 1q12
Cellular Component: transcription factor complex; nucleus; cytosol; MIS12/MIND type complex
Molecular Function: protein binding; leucine zipper domain binding; transcription coactivator activity
Biological Process: transcription from RNA polymerase II promoter; mitosis; regulation of transcription, DNA-dependent; cell division; mitotic cell cycle; chromosome segregation
Research Articles on PMF1
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Product Notes
The PMF1 pmf1 (Catalog #AAA9210983) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 109-135. The PMF1 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PMF1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the PMF1 pmf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PMF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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