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Western Blot (WB) (PLSCR4 Antibody (Center) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the PLSCR4 antibody detected the PLSCR4 protein (arrow).)

Rabbit anti-Mouse PLSCR4 Polyclonal Antibody | anti-PLSCR4 antibody

PLSCR4 Antibody (Center)

Gene Names
PLSCR4; TRA1
Reactivity
Mouse
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PLSCR4; Polyclonal Antibody; PLSCR4 Antibody (Center); Phospholipid scramblase 4; PL scramblase 4; Ca(2+)-dependent phospholipid scramblase 4; Cell growth-inhibiting gene 43 protein; TRA1; anti-PLSCR4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PLSCR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-151 amino acids from the Central region of human PLSCR4.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
122-151
Sequence Length
224
Applicable Applications for anti-PLSCR4 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(PLSCR4 Antibody (Center) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the PLSCR4 antibody detected the PLSCR4 protein (arrow).)

Western Blot (WB) (PLSCR4 Antibody (Center) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the PLSCR4 antibody detected the PLSCR4 protein (arrow).)

Immunohistochemistry (IHC)

(PLSCR4 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PLSCR4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (PLSCR4 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PLSCR4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-PLSCR4 antibody
PLSCR4 may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
Product Categories/Family for anti-PLSCR4 antibody
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Sahu, S.K., et al. Biochim. Biophys. Acta 1790(10):1274-1281(2009)
Py, B., et al. PLoS ONE 4 (3), E5006 (2009) :
Shibata, H., et al. J. Biol. Chem. 283(15):9623-9632(2008)
Wiedmer, T., et al. Biochim. Biophys. Acta 1467(1):244-253(2000)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37005
NCBI Official Full Name
phospholipid scramblase 4 isoform a
NCBI Official Synonym Full Names
phospholipid scramblase 4
NCBI Official Symbol
PLSCR4
NCBI Official Synonym Symbols
TRA1
NCBI Protein Information
phospholipid scramblase 4
UniProt Protein Name
Phospholipid scramblase 4
Protein Family
UniProt Gene Name
PLSCR4
UniProt Synonym Gene Names
PL scramblase 4
UniProt Entry Name
PLS4_HUMAN

Uniprot Description

PLSCR4: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Belongs to the phospholipid scramblase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q24

Cellular Component: integral to membrane; plasma membrane

Molecular Function: phospholipid scramblase activity; protein binding; enzyme binding; calcium ion binding; CD4 receptor binding; SH3 domain binding

Biological Process: phospholipid scrambling

Research Articles on PLSCR4

Similar Products

Product Notes

The PLSCR4 plscr4 (Catalog #AAA9204449) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 122-151. The PLSCR4 Antibody (Center) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PLSCR4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the PLSCR4 plscr4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLSCR4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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