Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using PLSCR3 antibody.)
Rabbit anti-Human, Mouse PLSCR3 Polyclonal Antibody | anti-PLSCR3 antibody
PLSCR3 Polyclonal Antibody
Reactivity
Human, Mouse
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
PLSCR3; Polyclonal Antibody; PLSCR3 Polyclonal Antibody; Phospholipid scramblase 3; PL scramblase 3; anti-PLSCR3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
PLSCR3 polyclonal antibody detects endogenous levels of PLSCR3 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
295
Applicable Applications for anti-PLSCR3 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant protein of human PLSCR3
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using PLSCR3 antibody.)
Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using PLSCR3 antibody.)
Related Product Information for anti-PLSCR3 antibody
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 32kDa
NCBI Official Full Name
phospholipid scramblase 3 isoform 1
UniProt Protein Name
Phospholipid scramblase 3
Protein Family
UniProt Gene Name
PLSCR3
UniProt Synonym Gene Names
PL scramblase 3
UniProt Entry Name
PLS3_HUMAN
Uniprot Description
PLSCR3: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Belongs to the phospholipid scramblase family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 17p13.1
Cellular Component: mitochondrial membrane; integral to membrane; plasma membrane
Molecular Function: phospholipid scramblase activity; protein binding; calcium ion binding; calcium-dependent protein binding; SH3 domain binding
Biological Process: cholesterol homeostasis; apoptosis; phospholipid scrambling; glucose homeostasis
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Product Notes
The PLSCR3 plscr3 (Catalog #AAA3009633) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PLSCR3 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PLSCR3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the PLSCR3 plscr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLSCR3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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