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Rabbit anti-Human PLIN5 Polyclonal Antibody | anti-PLIN5 antibody

PLIN5 Antibody, FITC conjugated

Gene Names
PLIN5; MLDP; LSDA5; LSDP5; OXPAT
Reactivity
Human
Applications
ELISA
Purity
>95%, Protein G purified
Synonyms
PLIN5; Polyclonal Antibody; PLIN5 Antibody; FITC conjugated; Perilipin-5; Lipid storage droplet protein 5; LSDP5; OXPAT; PAT-1; anti-PLIN5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
463
Applicable Applications for anti-PLIN5 antibody
ELISA (EIA)
Species
Human
Immunogen
Recombinant human Perilipin-5 protein
Conjugate
FITC
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-240627 / sc-240628
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-PLIN5 antibody
Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50,791 Da
NCBI Official Full Name
perilipin-5
NCBI Official Synonym Full Names
perilipin 5
NCBI Official Symbol
PLIN5
NCBI Official Synonym Symbols
MLDP; LSDA5; LSDP5; OXPAT
NCBI Protein Information
perilipin-5
UniProt Protein Name
Perilipin-5
Protein Family
UniProt Gene Name
PLIN5
UniProt Synonym Gene Names
LSDP5; OXPAT; PAT-1
UniProt Entry Name
PLIN5_HUMAN

NCBI Description

Members of the perilipin family, such as PLIN5, coat intracellular lipid storage droplets and protect them from lipolytic degradation (Dalen et al., 2007 [PubMed 17234449]).[supplied by OMIM, Feb 2010]

Uniprot Description

perilipin 5: Binds to lipid droplets and protects them from lipolytic degradation. Belongs to the perilipin family.

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cytoplasm; lipid particle; mitochondrion

Biological Process: negative regulation of fatty acid beta-oxidation; negative regulation of lipase activity; positive regulation of fatty acid beta-oxidation; positive regulation of lipase activity

Research Articles on PLIN5

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Product Notes

The PLIN5 plin5 (Catalog #AAA7045983) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PLIN5 Antibody, FITC conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PLIN5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the PLIN5 plin5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLIN5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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