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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded rat heart using MBS7602765 (PLEK antibody) at dilution of 1:200)

Rabbit PLEK Polyclonal Antibody | anti-PLEK antibody

PLEK Rabbit Polyclonal

Gene Names
PLEK; P47
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry, Immunoprecipitation
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
PLEK; Polyclonal Antibody; PLEK Rabbit Polyclonal; anti-PLEK antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
350
Applicable Applications for anti-PLEK antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
Immunogen
Pleckstrin
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded rat heart using MBS7602765 (PLEK antibody) at dilution of 1:200)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded rat heart using MBS7602765 (PLEK antibody) at dilution of 1:200)

Western Blot (WB)

(U-937 cells were subjected to SDS PAGE followed by western blot with MBS7602765 (PLEK antibody) at dilution of 1:1000)

Western Blot (WB) (U-937 cells were subjected to SDS PAGE followed by western blot with MBS7602765 (PLEK antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
40,125 Da
NCBI Official Full Name
PLEK
NCBI Official Synonym Full Names
pleckstrin
NCBI Official Symbol
PLEK
NCBI Official Synonym Symbols
P47
NCBI Protein Information
pleckstrin
UniProt Protein Name
Pleckstrin
Protein Family
UniProt Gene Name
PLEK
UniProt Synonym Gene Names
P47; p47
UniProt Entry Name
PLEK_HUMAN

Uniprot Description

pleckstrin: Major protein kinase C substrate of platelets.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 2p13.3

Cellular Component: cytoplasm; cytosol; extracellular region; membrane

Molecular Function: phosphatidylinositol-3,4-bisphosphate binding; protein binding; protein homodimerization activity; protein kinase C binding

Biological Process: actin cytoskeleton reorganization; cell projection organization and biogenesis; cortical actin cytoskeleton organization and biogenesis; hemopoietic progenitor cell differentiation; integrin-mediated signaling pathway; negative regulation of calcium-mediated signaling; negative regulation of G-protein coupled receptor protein signaling pathway; phosphatidylinositol metabolic process; phospholipase C inhibition; platelet degranulation; positive regulation of actin filament bundle formation; positive regulation of actin filament depolymerization; positive regulation of integrin activation; ruffle organization and biogenesis; vesicle docking during exocytosis

Research Articles on PLEK

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Product Notes

The PLEK plek (Catalog #AAA7602765) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PLEK Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PLEK can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the PLEK plek for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLEK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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