Western Blot (WB)
(Western Blot: Sample: Mouse Brain Tissue.)
Rabbit anti-Mouse Pleiotrophin (PTN) Polyclonal Antibody | anti-PTN antibody
Polyclonal Antibody to Pleiotrophin (PTN)
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot: Sample: Mouse Brain Tissue.)
Western Blot (WB)
(Western Blot: Sample: Mouse Brain Tissue.)
Western Blot (WB)
(Western Blot: Sample: Recombinant PTN, Mouse.)
Western Blot (WB)
(Western Blot: Sample: Recombinant PTN, Mouse.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Mouse Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P. Samples: Mouse Tissue))
NCBI and Uniprot Product Information
Uniprot Description
PTN: Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti- apoptotic signaling of PTN and regulation of cell proliferation. Belongs to the pleiotrophin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 6 B1|6 15.48 cM
Cellular Component: basement membrane; cell surface; cytoplasm; endoplasmic reticulum; extracellular region; extracellular space; membrane; neuromuscular junction; perinuclear region of cytoplasm; protein complex; proteinaceous extracellular matrix
Molecular Function: glycosaminoglycan binding; growth factor activity; heparin binding; protein kinase binding; proteoglycan binding
Biological Process: bone mineralization; learning; negative regulation of angiogenesis; negative regulation of cell migration; negative regulation of epithelial cell proliferation; negative regulation of membrane potential; ossification; positive regulation of apoptosis; positive regulation of cell division; positive regulation of cell proliferation; regulation of cell shape
Research Articles on PTN
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Product Notes
The PTN ptn (Catalog #AAA2002309) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Pleiotrophin (PTN) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Pleiotrophin (PTN) can be used in a range of immunoassay formats including, but not limited to, WB; IHC; ICC; IP. Western blotting: 0.5-2µg/mL Immunohistochemistry: 5-20µg/mL Immunocytochemistry: 5-20µg/mL Optimal working dilutions must be determined by end user. . Researchers should empirically determine the suitability of the PTN ptn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Pleiotrophin (PTN), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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