Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MBS7129520(PLCB3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))

Rabbit PLCB3 Polyclonal Antibody | anti-PLCB3 antibody

PLCB3 Antibody

Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
PLCB3; Polyclonal Antibody; PLCB3 Antibody; phospholipase C; beta 3; anti-PLCB3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Applicable Applications for anti-PLCB3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:1000-1:2000
WB: 1:200-1:1000
IHC: 1:50-1:200
Immunogen
Synthetic peptide of human PLCB3
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)-Paraffin

(The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MBS7129520(PLCB3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))

Immunohistochemistry (IHC)-Paraffin (The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MBS7129520(PLCB3 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200))

SDS-Page

(Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: A431 cells, PC3 cells, Primary antibody: MBS7129520(PLCB3 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes)

SDS-Page (Gel: 6%SDS-PAGE, Lysate: 40 ug, Lane 1-2: A431 cells, PC3 cells, Primary antibody: MBS7129520(PLCB3 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes)
Product Categories/Family for anti-PLCB3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
138,799 Da
NCBI Official Full Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform 1
NCBI Official Synonym Full Names
phospholipase C, beta 3 (phosphatidylinositol-specific)
NCBI Official Symbol
PLCB3
NCBI Protein Information
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; PLC beta 3; PLC-beta-3; phosphoinositide phospholipase C-beta-3
UniProt Protein Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
UniProt Gene Name
PLCB3
UniProt Synonym Gene Names
PLC-beta-3
UniProt Entry Name
PLCB3_HUMAN

NCBI Description

This gene encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Uniprot Description

PLCB3: a phosphatidylinositol-specific phospholipase C. Binds to calmodulin. The activated enzyme produces the second messenger molecules diacylglycerol and inositol 1,4,5-trisphosphate.

Protein type: EC 3.1.4.11; Carbohydrate Metabolism - inositol phosphate; Phospholipase

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: nucleoplasm; protein complex; membrane; cytosol

Molecular Function: calmodulin binding; signal transducer activity; calcium ion binding; phosphoinositide phospholipase C activity; phospholipase C activity

Biological Process: synaptic transmission; inositol phosphate metabolic process; regulation of systemic arterial blood pressure; lipid catabolic process

Research Articles on PLCB3

Similar Products

Product Notes

The PLCB3 plcb3 (Catalog #AAA7129520) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PLCB3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PLCB3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:1000-1:2000 WB: 1:200-1:1000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the PLCB3 plcb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLCB3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.