Western Blot (WB)
(Western blot analysis of PLC beta 3 (pS537) expression in HeLa PMA-treated (A), MCF7 UV-treated (B), mouse brain (C), rat brain (D) whole cell lysates.)
Rabbit PLC beta 3 (pS537) Polyclonal Antibody | anti-PLCB3 antibody
Anti-PLC beta 3 (pS537) Phospho Antibody
Western Blot (WB)
(Western blot analysis of PLC beta 3 (pS537) expression in HeLa PMA-treated (A), MCF7 UV-treated (B), mouse brain (C), rat brain (D) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of PLC beta 3 (pS537) expression in HeLa PMA-treated (A), MCF7 UV-treated (B), mouse brain (C), rat brain (D) whole cell lysates.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Uniprot Description
PLCB3: a phosphatidylinositol-specific phospholipase C. Binds to calmodulin. The activated enzyme produces the second messenger molecules diacylglycerol and inositol 1,4,5-trisphosphate.
Protein type: Carbohydrate Metabolism - inositol phosphate; Phospholipase; EC 3.1.4.11
Chromosomal Location of Human Ortholog: 11q13
Cellular Component: nucleoplasm; protein complex; membrane; cytosol
Molecular Function: calmodulin binding; signal transducer activity; calcium ion binding; phospholipase C activity; phosphoinositide phospholipase C activity
Biological Process: synaptic transmission; inositol phosphate metabolic process; regulation of systemic arterial blood pressure; lipid catabolic process
Research Articles on PLCB3
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Product Notes
The PLCB3 plcb3 (Catalog #AAA821418) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PLC beta 3 (pS537) Phospho Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PLC beta 3 (pS537) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB (1/500 - 1/1000). Researchers should empirically determine the suitability of the PLCB3 plcb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLC beta 3 (pS537), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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