Western Blot (WB)
(Western Blot: Sample: Lane1: Human A549 Cells; Lane2: Human Jurkat Cells.)
Rabbit anti-Human Platelet/Endothelial Cell Adhesion Molecule (PECAM1) Polyclonal Antibody | anti-PECAM1 antibody
Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1)
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.
Western Blot (WB)
(Western Blot: Sample: Lane1: Human A549 Cells; Lane2: Human Jurkat Cells.)
Western Blot (WB)
(Western Blot: Sample: Lane1: Human A549 Cells; Lane2: Human Jurkat Cells.)
Western Blot (WB)
(Western Blot: Sample: Recombinant PECAM1, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant PECAM1, Human.)
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Stomach Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Human Stomach Tissue))
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]
Uniprot Description
PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.
Protein type: Cell adhesion; Cell development/differentiation; Membrane protein, integral; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 17q23.3
Cellular Component: cell junction; extracellular exosome; extracellular space; integral component of membrane; membrane raft; plasma membrane; platelet alpha granule membrane; secretory granule membrane
Molecular Function: protein binding; protein homodimerization activity
Biological Process: cell recognition; cell-cell adhesion via plasma-membrane adhesion molecules; diapedesis; extracellular matrix organization; glomerular endothelium development; homophilic cell adhesion; leukocyte adhesion; leukocyte migration; neutrophil degranulation; neutrophil extravasation; phagocytosis; platelet degranulation; signal transduction
Research Articles on PECAM1
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Product Notes
The PECAM1 pecam1 (Catalog #AAA2004527) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Platelet/Endothelial Cell Adhesion Molecule (PECAM1) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Platelet/Endothelial Cell Adhesion Molecule (PECAM1) can be used in a range of immunoassay formats including, but not limited to, WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM. Western blotting: 0.5-2ug/ml Immunocytochemistry in formalin fixed cells: 5-20ug/ml Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml Immunohistochemistry in paraffin section: 5-20ug/ml Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml Optimal working dilutions must be determined by end user. . Researchers should empirically determine the suitability of the PECAM1 pecam1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Platelet/Endothelial Cell Adhesion Molecule (PECAM1), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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