Western Blot (WB)
(Western blot analysis of lysates from SH-SY5Y cell line (from left to right),using PLA2G4E Antibody(C15307). C15307 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.)
Rabbit PLA2G4E Polyclonal Antibody | anti-PLA2G4E antibody
PLA2G4E Antibody
Western Blot (WB)
(Western blot analysis of lysates from SH-SY5Y cell line (from left to right),using PLA2G4E Antibody(C15307). C15307 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.)
Western Blot (WB)
(Western blot analysis of lysates from SH-SY5Y cell line (from left to right),using PLA2G4E Antibody(C15307). C15307 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using PLA2G4E antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using PLA2G4E antibody.)
Zody M.C.,et al.Nature 440:671-675(2006).
NCBI and Uniprot Product Information
Uniprot Description
PLA2G4E: a calcium-dependent phospholipase A2 that catalyzes the release of arachidonic acid from membrane phospholipids. Selectively hydrolyzes glycerophospholipids in the sn-2 position. Translocates to lysosomal membranes in a calcium-dependent fashion. The N-terminal C2 domain associates with lipid membranes and mediates its regulation by presenting the active site to its substrate in response to elevations of cytosolic Ca2+. Two isoforms of the human protein are produced by alternative splicing.
Protein type: Lipid Metabolism - ether lipid; Lipid Metabolism - arachidonic acid; EC 3.1.1.4; Lipid Metabolism - glycerophospholipid; Phospholipase; Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - linoleic acid
Chromosomal Location of Human Ortholog: 15q15.1
Cellular Component: lysosomal membrane; cytosol
Molecular Function: phospholipase A2 activity; metal ion binding
Biological Process: phospholipid catabolic process; phospholipid metabolic process; glycerophospholipid biosynthetic process
Research Articles on PLA2G4E
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Product Notes
The PLA2G4E pla2g4e (Catalog #AAA9201620) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 428-456. AAA Biotech's PLA2G4E can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~ 1:500-1:1000. Researchers should empirically determine the suitability of the PLA2G4E pla2g4e for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLA2G4E, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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