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Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using PLA2G4E antibody. )

Rabbit anti-Human PLA2G4E Polyclonal Antibody | anti-PLA2G4E antibody

PLA2G4E Antibody

Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
PLA2G4E; Polyclonal Antibody; PLA2G4E Antibody; Cytosolic phospholipase A2 epsilon; EC 3.1.1.4; cPLA2-epsilon; Phospholipase A2 group IVE; anti-PLA2G4E antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid; Rabbit IgG In Phosphate Buffered Saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol.
Applicable Applications for anti-PLA2G4E antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:100
Immunogen
Synthesized peptide derived from internal of human PLA2G4E.
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using PLA2G4E antibody. )

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using PLA2G4E antibody. )
Product Categories/Family for anti-PLA2G4E antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
97,570 Da
NCBI Official Full Name
cytosolic phospholipase A2 epsilon
NCBI Official Synonym Full Names
phospholipase A2, group IVE
NCBI Official Symbol
PLA2G4E
NCBI Protein Information
cytosolic phospholipase A2 epsilon; cPLA2-epsilon
UniProt Protein Name
Cytosolic phospholipase A2 epsilon
Protein Family
UniProt Gene Name
PLA2G4E
UniProt Synonym Gene Names
cPLA2-epsilon
UniProt Entry Name
PA24E_HUMAN

Uniprot Description

PLA2G4E: a calcium-dependent phospholipase A2 that catalyzes the release of arachidonic acid from membrane phospholipids. Selectively hydrolyzes glycerophospholipids in the sn-2 position. Translocates to lysosomal membranes in a calcium-dependent fashion. The N-terminal C2 domain associates with lipid membranes and mediates its regulation by presenting the active site to its substrate in response to elevations of cytosolic Ca2+. Two isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid Metabolism - alpha-linolenic acid; Lipid Metabolism - glycerophospholipid; Phospholipase; Lipid Metabolism - linoleic acid; EC 3.1.1.4; Lipid Metabolism - ether lipid; Lipid Metabolism - arachidonic acid

Chromosomal Location of Human Ortholog: 15q15.1

Cellular Component: lysosomal membrane; cytosol

Molecular Function: phospholipase A2 activity; metal ion binding

Biological Process: phospholipid catabolic process; phospholipid metabolic process; glycerophospholipid biosynthetic process

Research Articles on PLA2G4E

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Product Notes

The PLA2G4E pla2g4e (Catalog #AAA7131315) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PLA2G4E Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PLA2G4E can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:50-1:100. Researchers should empirically determine the suitability of the PLA2G4E pla2g4e for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLA2G4E, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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