Western Blot (WB)
(PLA2G3 rabbit polyclonal antibody. Western Blot analysis of PLA2G3 expression in mouse liver.)
Rabbit anti-Human, Mouse PLA2G3 Polyclonal Antibody | anti-PLA2G3 antibody
PLA2G3 (Group 3 Secretory Phospholipase A2, Group III Secretory Phospholipase A2, GIII sPLA2, sPLA2-III, Phosphatidylcholine 2-acylhydrolase 3, SPLA2III) (FITC)
Gene Names
PLA2G3; SPLA2III; sPLA2-III; GIII-SPLA2
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
PLA2G3; Polyclonal Antibody; PLA2G3 (Group 3 Secretory Phospholipase A2; Group III Secretory Phospholipase A2; GIII sPLA2; sPLA2-III; Phosphatidylcholine 2-acylhydrolase 3; SPLA2III) (FITC); anti-PLA2G3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human PLA2G3. Species Crossreactivity: mouse.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Sequence Length
509
Applicable Applications for anti-PLA2G3 antibody
Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Full length human PLA2G3, aa1-509 (AAH25316.1).
Immunogen Sequence
MGVQAGLFGMLGFLGVALGGSPALRWYRTSCHLTKAVPGNPLGYLSFLAKDAQGLALIHARWDAHRRLQACSWEDEPELTAAYGALCAHETAWGSFIHTPGPELQRALATLQSQWEACRALEESPAGARKKRAAGQSGVPGGGHQREKRGWTMPGTLWCGVGDSAGNSSELGVFQGPDLCCREHDRCPQNISPLQYNYGIRNYRFHTISHCDCDTRFQQCLQNQHDSISDIVGVAFFNVLEIPCFVLEEQEACVAWYWWGGCRMYGTVPLARLQPRTFYNASWSSRATSPTPSSRSPAPPKPRQKQHLRKGPPHQKGSKRPSKANTTALQDPMVSPRLDVAPTGLQGPQGGLKPQGARWVCRSFRRHLDQCEHQIGPREIEFQLLNSAQEPLFHCNCTRRLARFLRLHSPPEVTNMLWELLGTTCFKLAPPLDCVEGKNCSRDPRAIRVSARHLRRLQQRRHQLQDKGTDERQPWPSEPLRGPMSFYNQCLQLTQAARRPDRQQKSWSQ
Conjugate
FITC
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(PLA2G3 rabbit polyclonal antibody. Western Blot analysis of PLA2G3 expression in mouse liver.)
Western Blot (WB)
(PLA2G3 rabbit polyclonal antibody. Western Blot analysis of PLA2G3 expression in mouse liver.)
Western Blot (WB)
(Western Blot analysis of PLA2G3 expression in transfected 293T cell line by PLA2G3 polyclonal antibody. Lane 1: PLA2G3 transfected lysate (57.2kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of PLA2G3 expression in transfected 293T cell line by PLA2G3 polyclonal antibody. Lane 1: PLA2G3 transfected lysate (57.2kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-PLA2G3 antibody
PLA2G3 belongs to the family of secreted phospholipase A2 (sPLA2; EC 3.1.1.4) proteins. These Ca(2+)-dependent lipolytic enzymes have a conserved Ca(2+)-binding loop and a his-asp dyad in the catalytic site (Murakami et al., 2003 [PubMed 12522102]).
Product Categories/Family for anti-PLA2G3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
Phospholipase A2, group III
NCBI Official Synonym Full Names
phospholipase A2 group III
NCBI Official Symbol
PLA2G3
NCBI Official Synonym Symbols
SPLA2III; sPLA2-III; GIII-SPLA2
NCBI Protein Information
group 3 secretory phospholipase A2
Protein Family
NCBI Description
This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids to release arachidonic acid and lysophospholipids. This enzyme acts as a negative regulator of ciliogenesis, and may play a role in cancer development by stimulating tumor cell growth and angiogenesis. This gene is associated with oxidative stress, and polymorphisms in this gene are linked to risk for Alzheimer's disease. [provided by RefSeq, Apr 2014]
Research Articles on PLA2G3
Similar Products
Product Notes
The PLA2G3 (Catalog #AAA6389661) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PLA2G3 (Group 3 Secretory Phospholipase A2, Group III Secretory Phospholipase A2, GIII sPLA2, sPLA2-III, Phosphatidylcholine 2-acylhydrolase 3, SPLA2III) (FITC) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PLA2G3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the PLA2G3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLA2G3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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