Rabbit PKP4/Plakophilin 4 Polyclonal Antibody | anti-PKP4 antibody

Anti-PKP4/Plakophilin 4 Antibody (aa1040-1068)

Cat. Num. AAA2401842

• Gene Names: PKP4; p0071
• Reactivity: Human; Predicted: Mouse
• Applications: Immunohistochemistry, Western Blot
• Purity: Protein A purified
• Synonyms: PKP4/Plakophilin 4; Polyclonal Antibody; Anti-PKP4/Plakophilin 4 Antibody (aa1040-1068); Rabbit Polyclonal to Human PKP4/Plakophilin 4; PKP4; p0071; Plakophilin 4; Catenin 4; Plakophilin-4; anti-PKP4 antibody

• Host: Rabbit
• Reactivity: Human; Predicted: Mouse
• Clonality: Polyclonal
• Specificity: This PKP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1040-1068 amino acids from the C-terminal region of human PKP4.
• Purity/Purification: Protein A purified
• Form/Format: PBS, 0.09% sodium azide.
• Sequence Length: 1192

• Applicable Applications for anti-PKP4 antibody: Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
• Application Notes: IHC-P: 1:100; WB: 1:1000
• Conjugation: Unconjugated
• Epitope: aa1040-1068
• Preparation and Storage: Short Term: Store at 4 degree C; Long Term: Aliquot and store at -20 degree C; Avoid freeze thaw cycles.

Immunohistochemistry (IHC)

(Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(PKP4 Antibody western blot of 293, CEM, HL-60, K562 cell line and mouse kidney, lung tissue lysates (35 ug/lane). The PKP4 antibody detected the PKP4 protein (arrow).)

Related Product Information for anti-PKP4 antibody

Armadillo-like proteins are characterized by a series of armadillo repeats, first defined in the Drosophila 'armadillo' gene product, that are typically 42 to 45 amino acids in length. these proteins can be divided into subfamilies based on their number of repeats, their overall sequence similarity, and the dispersion of the repeats throughout their sequences. Members of the p120(ctn)/plakophilin subfamily of Armadillo-like proteins, including CTNND1, CTNND2, PKP1, PKP2, PKP4, and ARVCF.

NCBI and Uniprot Product Information

• NCBI GI #: 53829374
• NCBI GeneID: 8502
• NCBI Accession #: NP_003619.2
• NCBI GenBank Nucleotide #: NM_003628.4
• UniProt Accession #: Q99569; Q86W91
• Molecular Weight: 127,144 Da
• NCBI Official Full Name: plakophilin-4 isoform a
• NCBI Official Synonym Full Names: plakophilin 4
• NCBI Official Symbol: PKP4
• NCBI Official Synonym Symbols: p0071
• NCBI Protein Information: plakophilin-4
• UniProt Protein Name: Plakophilin-4
• Protein Family: Plakophilin
• UniProt Gene Name: PKP4

NCBI Description

Armadillo-like proteins are characterized by a series of armadillo repeats, first defined in the Drosophila 'armadillo' gene product, that are typically 42 to 45 amino acids in length. These proteins can be divided into subfamilies based on their number of repeats, their overall sequence similarity, and the dispersion of the repeats throughout their sequences. Members of the p120(ctn)/plakophilin subfamily of Armadillo-like proteins, including CTNND1, CTNND2, PKP1, PKP2, PKP4, and ARVCF. PKP4 may be a component of desmosomal plaque and other adhesion plaques and is thought to be involved in regulating junctional plaque organization and cadherin function. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015]

Uniprot Description

Plays a role as a regulator of Rho activity during cytokinesis. May play a role in junctional plaques.