Western Blot (WB)
(Western blot analysis of PKG expression in 3T3 cell lysate.)
Rabbit PKG Polyclonal Antibody | anti-PKG antibody
PKG antibody
Applications
Western Blot
Purity
PKG antibody was purified by affinity chromatography
Synonyms
PKG; Polyclonal Antibody; PKG antibody; Polyclonal PKG; anti-PKG; cGMP dependent protein kinase 1 beta isozyme; KGPB; PRKG1 PR; cGKI alpha; CGKI; cGMP dependent protein kinase 1 alpha isozyme; cGKI beta; anti-PKG antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
PKG antibody was purified by affinity chromatography
Form/Format
Supplied in PBS buffer containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal
Concentration
500 ug/ml (varies by lot)
Sequence Length
733
Applicable Applications for anti-PKG antibody
Western Blot (WB)
Application Notes
WB: 0.5-4 ug/ml
Biological Significance
PKGs are cyclic GMP-dependent protein kinases that are classified into two types, PKGI and PKGII. Studies have shown that cGKs and cyclic AMP-dependent kinases are highly homologous protein kinase families with similar substrate specificities. Phosphorylation of cellular proteins by both families of kinases leads to alterations in calcium mobilization, protein phosphatase activity, ion channel function, gene transcription, smooth muscle contractility and platelet aggregation. However, recent studies using mice deficient in PKGs have shown that cGMP kinases regulate very specifically distinct pathways which are separate from those used by cyclic AMP kinases.
Cross-Reactivity
Human, Mouse, Rat, Bovine
Immunogen
PKG antibody was raised in Rabbit using synthetic peptide near the N-terminus of human PKG as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of PKG expression in 3T3 cell lysate.)
Western Blot (WB)
(Western blot analysis of PKG expression in 3T3 cell lysate.)
Related Product Information for anti-PKG antibody
Rabbit polyclonal PKG antibody
Product Categories/Family for anti-PKG antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
PKG
NCBI Official Symbol
LOC100533328
NCBI Protein Information
PKG
Similar Products
Product Notes
The PKG (Catalog #AAA835650) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PKG can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 0.5-4 ug/ml. Researchers should empirically determine the suitability of the PKG for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PKG, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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