Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Western Blot (WB) (All lanes : Anti-PIGC Antibody (C-Term) at 1:1000 dilutionLane 1: K562 whole cell lysateLane 2: MOLT-4 whole cell lysateLane 3: PC-3 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 34 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit PIGC Polyclonal Antibody | anti-PIGC antibody

PIGC Antibody (C-Term)

Gene Names
PIGC; GPI2
Reactivity
Human; Predicted Reactivity: Bovine, Mouse, Rat
Applications
Western Blot, ELISA
Synonyms
PIGC; Polyclonal Antibody; PIGC Antibody (C-Term); Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; 2.4.1.198; Phosphatidylinositol-glycan biosynthesis class C protein; PIG-C; GPI2; anti-PIGC antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human; Predicted Reactivity: Bovine, Mouse, Rat
Clonality
Polyclonal
Isotype
Ig
Specificity
This PIGC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 264-294 amino acids from human PIGC.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
297
Applicable Applications for anti-PIGC antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB:~~1:1000
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Cellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Antigen Type
Synthesized Peptide
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-PIGC Antibody (C-Term) at 1:1000 dilutionLane 1: K562 whole cell lysateLane 2: MOLT-4 whole cell lysateLane 3: PC-3 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 34 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (All lanes : Anti-PIGC Antibody (C-Term) at 1:1000 dilutionLane 1: K562 whole cell lysateLane 2: MOLT-4 whole cell lysateLane 3: PC-3 whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 34 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-PIGC antibody
Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
Product Categories/Family for anti-PIGC antibody
References
Inoue N.,et al.Biochem. Biophys. Res. Commun. 226:193-199 (1996). Hong Y.,et al.Genomics 44:347-349 (1997). Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. Ebert L.,et al.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases. Gregory S.G.,et al.Nature 441:315-321 (2006).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
33583 Da
NCBI Official Full Name
phosphatidylinositol N-acetylglucosaminyltransferase subunit C
NCBI Official Synonym Full Names
phosphatidylinositol glycan anchor biosynthesis class C
NCBI Official Symbol
PIGC
NCBI Official Synonym Symbols
GPI2
NCBI Protein Information
phosphatidylinositol N-acetylglucosaminyltransferase subunit C
UniProt Protein Name
Phosphatidylinositol N-acetylglucosaminyltransferase subunit C
UniProt Gene Name
PIGC
UniProt Synonym Gene Names
GPI2; PIG-C
UniProt Entry Name
PIGC_HUMAN

NCBI Description

This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI) lipid anchor biosynthesis. The GPI lipid anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. The encoded protein is one subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. Two alternatively spliced transcripts that encode the same protein have been found for this gene. A pseudogene on chromosome 11 has also been characterized. [provided by RefSeq, Jul 2008]

Uniprot Description

PIGC: Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. Belongs to the PIGC family.

Protein type: EC 2.4.1.198; Transferase; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Membrane protein, multi-pass; Membrane protein, integral; Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 1q23-q25

Cellular Component: endoplasmic reticulum membrane; glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex; integral to membrane

Molecular Function: catalytic activity; phosphatidylinositol N-acetylglucosaminyltransferase activity

Biological Process: GPI anchor biosynthetic process; preassembly of GPI anchor in ER membrane

Research Articles on PIGC

Similar Products

Product Notes

The PIGC pigc (Catalog #AAA9217246) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PIGC Antibody (C-Term) reacts with Human; Predicted Reactivity: Bovine, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PIGC can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB:~~1:1000. Researchers should empirically determine the suitability of the PIGC pigc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIGC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.