Immunohistochemistry (IHC)
(Immunohistochemistry (IHC) analyzes of PIG11 (P93) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.)
Rabbit PIG11 Polyclonal Antibody | anti-PIG11 antibody
PIG11 (P93) Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
PIG11; Polyclonal Antibody; PIG11 (P93) Polyclonal Antibody; Tumor protein p53-inducible protein 11; p53-induced gene 11 protein; TP53I11; anti-PIG11 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
PIG11 (P93) polyclonal antibody detects endogenous levels of PIG11 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
189
Applicable Applications for anti-PIG11 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:200
Immunogen
Synthetic peptide, corresponding to amino acids 71-120 of Human PIG11.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry (IHC) analyzes of PIG11 (P93) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.)
Immunohistochemistry (IHC)
(Immunohistochemistry (IHC) analyzes of PIG11 (P93) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.)
Related Product Information for anti-PIG11 antibody
PIG11 (p53-induced gene 11 protein), also known as TP53I11, is a 177 amino acid tumor suppressor belonging to the p53-induced protein gene (PIG) family. The PIG gene family encodes redox-controlling proteins that are involved in p53 tumor suppressor activity. It is suggested that PIG11 is involved in arsenic trioxide As(2)O(3)-induced apoptosis in certain cell lines and may play a significant role in tumor suppression through promotion of cell apoptosis. The gene encoding PIG11 maps to human chromosome 11, which houses over 1, 400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 21kDa
NCBI Official Full Name
tumor protein p53-inducible protein 11 isoform a
UniProt Protein Name
Tumor protein p53-inducible protein 11
Protein Family
UniProt Gene Name
TP53I11
UniProt Synonym Gene Names
PIG11
UniProt Entry Name
P5I11_HUMAN
Uniprot Description
TP53I11: Induced by TP53/p53.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 11p11.2
Cellular Component: integral to membrane
Biological Process: negative regulation of cell proliferation; response to stress
Similar Products
Product Notes
The PIG11 tp53i11 (Catalog #AAA3001787) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PIG11 (P93) Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PIG11 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the PIG11 tp53i11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIG11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
