Western Blot (WB)
(Western blot analysis of PICH expression in Jurkat (A), A549 (B) whole cell lysates.)
Rabbit anti-Human PICH Polyclonal Antibody | anti-PICH antibody
Anti-PICH Antibody
Western Blot (WB)
(Western blot analysis of PICH expression in Jurkat (A), A549 (B) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of PICH expression in Jurkat (A), A549 (B) whole cell lysates.)
NCBI and Uniprot Product Information
Uniprot Description
PICH: DNA helicase that acts as an essential component of the spindle assembly checkpoint. Contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. Acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. Interacts with PLK1, which phosphorylates it. Both proteins are mutually dependent on each other for correct subcellular localization. Belongs to the SNF2/RAD54 helicase family.
Protein type: Helicase; EC 3.6.4.12
Chromosomal Location of Human Ortholog: Xq13.1
Cellular Component: nucleoplasm; centrosome; membrane; cytoplasm; plasma membrane; cytosol
Molecular Function: protein binding; DNA binding; helicase activity; ATP binding
Biological Process: mitosis; metabolic process; cell division; mitotic cell cycle
Research Articles on PICH
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Product Notes
The PICH ercc6l (Catalog #AAA8306593) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PICH Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PICH can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the PICH ercc6l for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PICH, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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