Rabbit anti-Human PIAS4 Polyclonal Antibody | anti-PIAS4 antibody
PIAS4 Antibody, HRP Conjugated
Gene Names
PIAS4; PIASY; Piasg; ZMIZ6; PIAS-gamma
Reactivity
Human
Applications
ELISA
Purity
>95%Protein G Purified
Synonyms
PIAS4; Polyclonal Antibody; PIAS4 Antibody; HRP Conjugated; E3 SUMO-protein ligase PIAS4; PIASy; Protein inhibitor of activated STAT protein 4; Protein inhibitor of activated STAT protein gamma; PIAS-gamma; RING-type E3 ubiquitin transferase PIAS4; PIASG; anti-PIAS4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%
Protein G Purified
Protein G Purified
Form/Format
Liquid
Sequence Length
510
Applicable Applications for anti-PIAS4 antibody
ELISA (EIA)
Immunogen Species
Human
Immunogen
Recombinant Human E3 SUMO-protein ligase PIAS4 protein (66-241AA)
Conjugate
HRP
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at-20 degree C or-80 degree C. Avoid repeated freeze.
Product Categories/Family for anti-PIAS4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
56,504 Da
NCBI Official Full Name
E3 SUMO-protein ligase PIAS4
NCBI Official Synonym Full Names
protein inhibitor of activated STAT 4
NCBI Official Symbol
PIAS4
NCBI Official Synonym Symbols
PIASY; Piasg; ZMIZ6; PIAS-gamma
NCBI Protein Information
E3 SUMO-protein ligase PIAS4
UniProt Protein Name
E3 SUMO-protein ligase PIAS4
Protein Family
UniProt Gene Name
PIAS4
UniProt Synonym Gene Names
PIASG; PIAS-gamma
Uniprot Description
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.
Research Articles on PIAS4
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Product Notes
The PIAS4 pias4 (Catalog #AAA7114251) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PIAS4 Antibody, HRP Conjugated reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PIAS4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the PIAS4 pias4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIAS4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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