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Western Blot (WB) (Western blot analysis of PI 3 Kinase Class 3 expression in 293T cell lysate.)

Rabbit PI 3 Kinase Class 3 Polyclonal Antibody | anti-PIK3C3 antibody

Anti-PI 3 Kinase Class 3 Rabbit pAb

Gene Names
PIK3C3; VPS34; Vps34; hVps34
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Affinity Chromatography
Synonyms
PI 3 Kinase Class 3; Polyclonal Antibody; Anti-PI 3 Kinase Class 3 Rabbit pAb; Phosphatidylinositol 3-kinase catalytic subunit type 3 (EC:2.7.1.137); PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3; Phosphatidylinositol 3-kinase p100 subunit; Phosphoinositide-3-kinase class 3; hVps34; anti-PIK3C3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
PI 3 Kinase Class 3 Antibody detects endogenous levels of total PI 3 Kinase Class 3
Purity/Purification
Affinity Chromatography
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
887
Applicable Applications for anti-PIK3C3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:200
Immunogen
A synthesized peptide derived from human PI 3 Kinase Class 3
Subcellular Location
Nucleus
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.

Western Blot (WB)

(Western blot analysis of PI 3 Kinase Class 3 expression in 293T cell lysate.)

Western Blot (WB) (Western blot analysis of PI 3 Kinase Class 3 expression in 293T cell lysate.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human kidney, using PI 3 Kinase Class 3 Antibody.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human kidney, using PI 3 Kinase Class 3 Antibody.)
Related Product Information for anti-PIK3C3 antibody
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
100kDa
NCBI Official Full Name
phosphatidylinositol 3-kinase catalytic subunit type 3 isoform 1
NCBI Official Synonym Full Names
phosphatidylinositol 3-kinase catalytic subunit type 3
NCBI Official Symbol
PIK3C3
NCBI Official Synonym Symbols
VPS34; Vps34; hVps34
NCBI Protein Information
phosphatidylinositol 3-kinase catalytic subunit type 3
UniProt Protein Name
Phosphatidylinositol 3-kinase catalytic subunit type 3
UniProt Gene Name
PIK3C3
UniProt Synonym Gene Names
PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3

Uniprot Description

Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes ().

Research Articles on PIK3C3

Similar Products

Product Notes

The PIK3C3 pik3c3 (Catalog #AAA477851) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PI 3 Kinase Class 3 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PI 3 Kinase Class 3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the PIK3C3 pik3c3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PI 3 Kinase Class 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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