Testing Data
Rabbit phospho-MST4 + MST3 + STK25 Polyclonal Antibody | anti-MST4+MST3+STK25 antibody
phospho-MST4 + MST3 + STK25 (Thr178 + Thr190 + Thr174) Polyclonal Antibody
Gene Names
STK25; SOK1; YSK1
Reactivity
Human, Mouse, Rat, Cow, Horse, Sheep
Applications
Western Blot
Purity
affinity purified by Protein A
Synonyms
phospho-MST4 + MST3 + STK25; Polyclonal Antibody; phospho-MST4 + MST3 + STK25 (Thr178 + Thr190 + Thr174) Polyclonal Antibody; phospho-MST4+MST3+STK25(phospho T178 + T190 + T174); p-MST4 + MST3 + STK25 (phospho T178 + T190 + T174); Mammalian STE20 like protein kinase 3; Mammalian Ste20 like protein kinase 4; Mammalian sterile 20 like 4; MASK; mess1; MGC94619; MST 3; MST 4; MST; Mst2; MST3 and SOK1 related kinase; MST3; MST3B; OTTHUMP00000018592; OTTHUMP00000018593; Protein kinase homolog serine/threonine kinase 3 (Ste20 yeast homolog); RGD1563568; RP11-111L24.5; Serine/threonine kinase 24 (STE20 homolog yeast); Serine/threonine kinase 24; Serine/threonine kinase 25; Serine/threonine protein kinase 24; Serine/threonine protein kinase MASK; Serine/threonine protein kinase MST 4; Serine/threonine protein kinase MST4; SOK1; STE20; Ste20 like; Ste20 like kinase; STE20 like kinase 3; STE20 like kinase MST 4; STE20 like kinase MST3; STE20 like kinase MST4; Ste20 yeast homolog; Ste20/oxidant stress response kinase 1; Sterile 20 (oxidant stress response kinase 1); sterile 20 like kinase 3; Sterile 20/oxidant stress-response kinase 1; STK3; Yeast Sps1/Ste20 related kinase 1; YSK1; anti-MST4+MST3+STK25 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Horse, Sheep
Clonality
Polyclonal
Specificity
phospho-MST4 + MST3 + STK25 (Thr178 + Thr190 + Thr174) Polyclonal Antibody detects endogenous levels of phospho-MST4 + MST3 + STK25 protein only when phosphorylated at Thr178 + Thr190 + Thr174
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Applicable Applications for anti-MST4+MST3+STK25 antibody
Western Blot (WB)
Application Notes
WB: 1:500-2000
Immunogen
KLH conjugated synthesised phosphopeptide derived from human MST4/MST3/STK25 around the phosphorylation site of Thr178/Thr190/Thr174
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Testing Data
Testing Data
Related Product Information for anti-MST4+MST3+STK25 antibody
Novel human Ste20-related kinase Mst4 is biologically active in the activation of MEK/ERK pathway and in mediating cell growth and transformation. It is pro apoptotic and is highly expressed in placenta, thymus, and peripheral blood leukocytes. Interaction with Golgi matrix protein GOLGA2 results in autophosphorylation on Thr-178, possibly as a consequence of stabilization of dimer formation. This may also be activated by C terminal cleavage. MST3 or Mammalian Sterile 20-like kinase 3 is a member of the germinal center kinase-III family. MST3 contains a conserved kinase domain at its NH(2)-terminus and a regulatory domain at its COOH-terminus. Caspase-mediated cleavage of the regulatory domain of MST3 activates its intrinsic kinase activity and leads to nuclear translocation. Expression of COOH-terminal truncated MST3 in cells results in DNA fragmentation and induction of apoptosis. It can inhibit cell migration in a fashion dependent on autophosphorylation and can regulate paxillin phosphorylation through tyrosine phosphatase PTP-PEST. Mitogen activated protein kinase cascades have been conserved throughout evolution. In mammals, these cascades allow responses to complex stimuli such as growth factors and inflammatory cytokines. In yeast, STK25 functions upstream of the MAPK cascade.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
37,297 Da
NCBI Official Full Name
serine/threonine-protein kinase 25 isoform 1
NCBI Official Synonym Full Names
serine/threonine kinase 25
NCBI Official Symbol
STK25
NCBI Official Synonym Symbols
SOK1; YSK1
NCBI Protein Information
serine/threonine-protein kinase 25; Ste20, yeast homolog; ste20-like kinase; ste20/oxidant stress response kinase 1; sterile 20/oxidant stress-response kinase 1
UniProt Protein Name
Serine/threonine-protein kinase 25
UniProt Gene Name
STK25
UniProt Synonym Gene Names
SOK1; YSK1; SOK-1; Ste20/oxidant stress response kinase 1
UniProt Entry Name
STK25_HUMAN
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Product Notes
The MST4+MST3+STK25 stk25 (Catalog #AAA3015185) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The phospho-MST4 + MST3 + STK25 (Thr178 + Thr190 + Thr174) Polyclonal Antibody reacts with Human, Mouse, Rat, Cow, Horse, Sheep and may cross-react with other species as described in the data sheet. AAA Biotech's phospho-MST4 + MST3 + STK25 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-2000. Researchers should empirically determine the suitability of the MST4+MST3+STK25 stk25 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "phospho-MST4 + MST3 + STK25, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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