Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Rat liver using Phospho-Histone H2A (S129) Polyclonal Antibody at dilution of 1:100 (40x lens).)
Rabbit anti-Human, Rat Phospho-Histone H2A (S129) Polyclonal Antibody | anti-H2A antibody
Phospho-Histone H2A (S129) Polyclonal Antibody
Gene Names
HTA1; H2A1; SPT11
Reactivity
Human, Rat
Applications
Immunohistochemistry
Purity
Affinity purification
Synonyms
Phospho-Histone H2A (S129); Polyclonal Antibody; Phospho-Histone H2A (S129) Polyclonal Antibody; H2A1; SPT11; anti-H2A antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-H2A antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:200
Immunogen
A phospho synthetic peptide corresponding to residues surrounding S129 of human Histone H2A
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Rat liver using Phospho-Histone H2A (S129) Polyclonal Antibody at dilution of 1:100 (40x lens).)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Rat liver using Phospho-Histone H2A (S129) Polyclonal Antibody at dilution of 1:100 (40x lens).)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human breast cancer using Phospho-Histone H2A (S129) Polyclonal Antibody at dilution of 1:100 (40x lens).)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human breast cancer using Phospho-Histone H2A (S129) Polyclonal Antibody at dilution of 1:100 (40x lens).)
Related Product Information for anti-H2A antibody
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Product Categories/Family for anti-H2A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
13,989 Da
NCBI Official Full Name
histone H2A
NCBI Official Symbol
HTA1
NCBI Official Synonym Symbols
H2A1; SPT11
NCBI Protein Information
histone H2A
UniProt Protein Name
Histone H2A.1
UniProt Gene Name
HTA1
UniProt Synonym Gene Names
H2A1; SPT11
Uniprot Description
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Research Articles on H2A
Similar Products
Product Notes
The H2A hta1 (Catalog #AAA2567072) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Phospho-Histone H2A (S129) Polyclonal Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Phospho-Histone H2A (S129) can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the H2A hta1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Phospho-Histone H2A (S129), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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