Western Blot (WB)
(Western Blot (WB) analysis of PGRMC2 polyclonal antibody at 1:500 dilutionLane1:Hela cell lysateLane2:H9C2 cell lysateLane3:Rat brain tissue lysate)
Rabbit PGRMC2 Polyclonal Antibody | anti-PGRMC2 antibody
PGRMC2 Polyclonal Antibody
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunocytochemistry
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
PGRMC2; Polyclonal Antibody; PGRMC2 Polyclonal Antibody; Membrane-associated progesterone receptor component 2; Progesterone membrane-binding protein; Steroid receptor protein DG6; DG6; PMBP; anti-PGRMC2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
PGRMC2 polyclonal antibody detects endogenous levels of PGRMC2 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
223
Applicable Applications for anti-PGRMC2 antibody
Western Blot (WB), Immunocytochemistry (ICC)
Application Notes
WB: 1:500-1:1000
ICC: 1:50-1:200
ICC: 1:50-1:200
Immunogen
Synthetic peptide, corresponding to the 178-223 of Human PGRMC2.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of PGRMC2 polyclonal antibody at 1:500 dilutionLane1:Hela cell lysateLane2:H9C2 cell lysateLane3:Rat brain tissue lysate)
Western Blot (WB)
(Western Blot (WB) analysis of PGRMC2 polyclonal antibody at 1:500 dilutionLane1:Hela cell lysateLane2:H9C2 cell lysateLane3:Rat brain tissue lysate)
Related Product Information for anti-PGRMC2 antibody
PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas.
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
~ 24kDa
NCBI Official Full Name
Membrane-associated progesterone receptor component 2
UniProt Protein Name
Membrane-associated progesterone receptor component 2
Protein Family
UniProt Gene Name
PGRMC2
UniProt Synonym Gene Names
DG6; PMBP
UniProt Entry Name
PGRC2_HUMAN
Uniprot Description
PGRMC2: Receptor for steroids (Potential). Belongs to the cytochrome b5 family. MAPR subfamily.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 4q26
Cellular Component: membrane; integral to membrane; endomembrane system
Molecular Function: heme binding; steroid hormone receptor activity; steroid binding
Biological Process: steroid hormone mediated signaling
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Product Notes
The PGRMC2 pgrmc2 (Catalog #AAA3006081) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PGRMC2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PGRMC2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC). WB: 1:500-1:1000 ICC: 1:50-1:200. Researchers should empirically determine the suitability of the PGRMC2 pgrmc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PGRMC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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