Rabbit anti-Human, Mouse PGM1 Polyclonal Antibody | anti-PGM1 antibody

PGM1 Antibody (C-Term)

Cat. Num. AAA9216091

• Gene Names: PGM1; CDG1T; GSD14
• Reactivity: Human, Mouse
• Applications: Western Blot
• Synonyms: PGM1; Polyclonal Antibody; PGM1 Antibody (C-Term); Purified Rabbit Polyclonal Antibody (Pab); Phosphoglucomutase-1; PGM 1; Glucose phosphomutase 1; anti-PGM1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: Ig
• Specificity: This PGM1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 469-501 amino acids from human PGM1.
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Sequence Length: 580

• Applicable Applications for anti-PGM1 antibody: Western Blot (WB)
• Application Notes: WB ~~ 1:2000; WB ~~ 1:2000
• Antigen Source: Human
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-PGM1 Antibody (C-Term) at 1:2000 dilutionLane 1: mouse heart lysatesLane 2: Jurkat whole cell lysatesLane 3: human liver lysatesLane 4: NIH/3T3 whole cell lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 61 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB)

(All lanes : Anti-PGM1 Antibody (C-Term) at 1:2000 dilutionLane 1: mouse brain lysatesLane 2: mouse heart lysatesLane 3: human liver lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 61 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Related Product Information for anti-PGM1 antibody

This enzyme participates in both the breakdown and synthesis of glucose.

Product Categories/Family for anti-PGM1 antibody

Crown Antibodies; Metabolism; Signal Transduction

References

Whitehouse D.B.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:411-415(1992). Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). Gregory S.G.,et al.Nature 441:315-321(2006). Putt W.,et al.Biochem. J. 296:417-422(1993).

NCBI and Uniprot Product Information

• NCBI GI #: 290463102
• NCBI GeneID: 5236
• NCBI Accession #: NP_001166289.1
• NCBI GenBank Nucleotide #: NM_001172818.1
• UniProt Accession #: P36871; Q16105; Q16106; Q5BKZ9; Q6NW22; Q86U74; Q96J40; Q9NTY4; B2R5N9; B4DPV0
• Molecular Weight: 61449
• NCBI Official Full Name: phosphoglucomutase-1 isoform 2
• NCBI Official Synonym Full Names: phosphoglucomutase 1
• NCBI Official Symbol: PGM1
• NCBI Official Synonym Symbols: CDG1T; GSD14
• NCBI Protein Information: phosphoglucomutase-1
• UniProt Protein Name: Phosphoglucomutase-1
• Protein Family: Phosphoglucomutase
• UniProt Gene Name: PGM1
• UniProt Synonym Gene Names: PGM 1
• UniProt Entry Name: PGM1_HUMAN

NCBI Description

The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Mar 2010]

Uniprot Description

This enzyme participates in both the breakdown and synthesis of glucose.