Western Blot (WB)
(PGLYRP4 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PGLYRP4 antibody detected the PGLYRP4 protein (arrow).)
Rabbit anti-Human PGLYRP4 Polyclonal Antibody | anti-PGLYRP4 antibody
PGLYRP4, ID (PGLYRP4, PGRPIB, Peptidoglycan recognition protein 4, Peptidoglycan recognition protein I-beta, Peptidoglycan recognition protein intermediate beta)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Western Blot (WB)
(PGLYRP4 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PGLYRP4 antibody detected the PGLYRP4 protein (arrow).)
Western Blot (WB)
(PGLYRP4 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PGLYRP4 antibody detected the PGLYRP4 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
Peptidoglycan recognition proteins, such as PGRPI-beta, are part of the innate immune system and recognize peptidoglycan, a ubiquitous component of bacterial cell walls.[supplied by OMIM, Apr 2004]
Uniprot Description
PGLYRP4: Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram- negative bacteria, and has bacteriostatic activity towards Gram- negative bacteria. Plays a role in innate immunity. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 1q21
Cellular Component: membrane; extracellular region; intracellular
Molecular Function: peptidoglycan receptor activity; peptidoglycan binding; zinc ion binding; N-acetylmuramoyl-L-alanine amidase activity
Biological Process: defense response to Gram-positive bacterium; negative regulation of natural killer cell differentiation during immune response; detection of bacterium; negative regulation of interferon-gamma production; innate immune response; pattern recognition receptor signaling pathway; peptidoglycan catabolic process
Research Articles on PGLYRP4
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Product Notes
The PGLYRP4 pglyrp4 (Catalog #AAA6000744) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PGLYRP4, ID (PGLYRP4, PGRPIB, Peptidoglycan recognition protein 4, Peptidoglycan recognition protein I-beta, Peptidoglycan recognition protein intermediate beta) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PGLYRP4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the PGLYRP4 pglyrp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PGLYRP4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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